Supported by the Education Department of Heilongjiang Province,China,No.11521124
BACKGROUND The digestive tract is the maximal immunizing tissue in the body, and mucosal integrity and functional status of the gut is very important to maintain a healthy organism. Severe infection is one of the most...
Supported by The NOVO Nordisk foundation;the Aarhus University Research Foundation;Clinical Institute,Aarhus University,Denmark
AIM: To study the effect of a new anti-CD163-dexamethasone conjugate targeting activated macrophages on the hepatic acute phase response in rats. METHODS: Wistar rats were injected intravenous with either the CD163 ta...
supported by a grant from the National Basic Research Program(973)of China(2013CB531401)
BACKGROUND: Acute liver injury is a common clinical disorder associated with intestinal barrier injury and disturbance of intestinal microbiota. Probiotic supplementation has been reported to reduce liver injury; how...
Background A proinflammatory milieu emerging in the lung due to neutrophil accumulation and activation is a key in the pathogenesis of acute lung injury (ALI).15-deoxy-△12,14-prostaglandin J2 (15d-PGJ2),one of th...
supported by Foundation of Health Department of Jilin Province(No.2009Z072)
Summary: The protective effect of erythropoietin (EPO) on tissues following ischemia and reperfusion injuries remains poorly understood. We aimed to investigate the effect of EPO in preventing en- dotoxin-induced o...
AIM: To explore the change of intestinal mucosa barrier function in the progress of non-alcoholic steatohepatitis (NASH) in rats. METHODS: Thirty-two Sprague-Dawley (SD) rats were randomly divided into control group a...
awards to University Academic Leaders granted by the Government of Shanxi Province of China to Hui-Ying Zhang and partially by the National Institute of Alcohol Abuse and Alcoholism of United States, grant R01 AA014428 to Cheng Ji
AIM: To develop and characterize a practical model of Hepatopulmonary syndrome. (HPS) in rats.METHODS: The experimental animals were randomized into five feeding groups: (1) control (fed standard diet), (2)...
Objective : To investigate the effect of Radix Paeoniae Rubra (RPR) on the expression of heme oxygenase ( HO- 1 ) and induced nitric oxide synthase ( iNOS ) in endotoxin- induced acute lung injury in rats and i...
This study was supported by grants from the NationalBasic Research Program (973) of China ( No. 2003CB515506),Postdoctoral Fund of China (20040350233), and Research Grantawarded by the First Affiliated Hospital, Zhejiang UniversitySchool of Medicine, Hangzhou, China.
BACKGROUND: Hepatic ischemia/reperfusion injury may induce intestinal microflora imbalance. Salvia miltiorrhiza is effective in promoting blood circulation and counteracting peroxidation in tissues. The aim of the pre...