云南高校图书馆联盟文献共享服务平台- INSULIN-LIKE

INSULIN-LIKE: 作品数：58被引量：346H指数：10; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：李奕萍张新余波张新华姜恩泽更多>>; 相关机构：绵阳市第三人民医院第二军医大学南京军区南京总医院常州市第一人民医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金国家重点基础研究发展计划唐山市科技局指令性项目更多>>

Hyperglycemia and reduced adiposity of streptozotocin-induced diabetic mice are not alleviated by oral benzylamine supplementation: 《World Journal of Diabetes》2022年第9期752-764,共13页Christian Carpéné Kristiyan Stiliyanov Atanasov Francisco Les Josep Mercader Barcelo; BACKGROUND Benzylamine(Bza)oral administration delays the onset of hyperglycemia in insulin-resistant db-/-mice;a genetic model of obesity and type 2 diabetes.AIM To extend the antihyperglycemic properties of oral ben...; 关键词：Diabetes ADIPOCYTES Amine oxidases Insulin-like agents Glucose transport POLYDIPSIA

Associations between Placental Insulin-Like Growth Factor-1 Gene Expression, DNA Methylation and Intrauterine Growth Restriction: 《Health》2020年第3期270-280,共11页Xiaojuan Li Baifeng Yu Xueli Wu Jiye Zhang Caihong Jia Zhuo Wang Qiaomiao Zhou Hongtao Zhou Guohui Yi Xinping Chen Shengmiao Fu; Intrauterine growth restriction (IUGR) is a common fetal development disorder which has great impact on neonatal health. Insulin-like growth factor-1 (IGF1) has an important role in regulating fetal growth. Whether IG...; 关键词：PLACENTAL INSULIN-LIKE Growth Factor-1 IUGR

Association of IGF1R polymorphisms(rs1546713) with susceptibility to age-related cataract in a Han Chinese population被引量：1: 《International Journal of Ophthalmology(English edition)》2020年第3期374-381,共8页Yi-Lei Cui Xiao-Ning Yu Xin Zhang Ye-Lei Tang Xia-Jing Tang Hao Yang Xi-Yuan Ping Jing Wu Qi-Chuan Yin Jia-Yue Zhou Xia-Yan Xu Xing-Chao Shentu; Supported by the National Natural Science Foundation of China(No.81670834,No.81970781,No.81800807,No.81800869);the Natural Science Foundation of Zhejiang Province(No.LY17H090004).; AIM:To explore the susceptible association between the insulin-like growth factor-1 receptor(IGF1 R)single nucleotide polymorphism(SNP)and age-related cataract(ARC),and investigate the underlying mechanisms in human l...; 关键词：INSULIN-LIKE growth factor-1 receptor AGE-RELATED CATARACT single NUCLEOTIDE polymorphism

Insulin-like growth factor 2 mRNA-binding protein 1 promotes cell proliferation via activation of AKT and is directly targeted by microRNA-494 in pancreatic cancer被引量：8: 《World Journal of Gastroenterology》2019年第40期6063-6076,共14页Bai-Shun Wan Ming Cheng Ling Zhang; Supported by the National Natural Science Foundation of China,No.61802350; BACKGROUND Studies have shown that insulin-like growth factor 2 mRNA-binding protein 1(IGF2BP1)plays critical roles in the genesis and development of human cancers.AIM To investigate the clinical significance and role...; 关键词：PANCREATIC cancer INSULIN-LIKE growth factor 2 mRNA-binding protein 1 Proliferation MicroRNA-494

Respiratory Disorders in Acromegalic Patients: 《International Journal of Clinical Medicine》2019年第10期553-564,共12页Valeria Mercuri Tullia Villani Denise Costa Michela Mordenti Tania D’Amico Paolo Palange Patrizia Gargiulo; Purpose: To evaluate the prevalence and clinical performance of obstructive sleep apnoea syndrome (OSAS) in acromegalic patients, focusing on the possible correlation between alterations of pulmonary microcirculation ...; 关键词：ACROMEGALY OBSTRUCTIVE Sleep APNOEA Syndrome GROWTH Hormone INSULIN-LIKE GROWTH Factor 1 Carbon MONOXIDE Diffusing Capacity

Picropodophyllin inhibits type I endometrial cancer cell proliferation via disruption of the PI3K/Akt pathway被引量：1: 《Acta Biochimica et Biophysica Sinica》2019年第7期753-760,共8页Lin Dong Meirong Du Qianzhou Lv; The type-I insulin-like growth factor receptor (IGF-IR) is overexpressed in endometrial cancer. High IGF-IR expression was considered as an important prognostic factor for tumor progression. The purpose of this study ...; 关键词：ENDOMETRIAL cancer picropodophyllin type-I INSULIN-LIKE growth factor receptor cell PROLIFERATION tissue chip

Frailty Prevalence and Characteristics in Older Patients with Type 2 Diabetes: 《Journal of Diabetes Mellitus》2019年第2期31-38,共8页Takahisa Tanikawa Sayuri Sable-Morita Haruhiko Tokuda Hidenori Arai; Background: Older diabetic patients are more likely to be frail than those who do not have diabetes. Frailty is an important risk factor for both mortality and disability in older patients with type 2 diabetes. Howeve...; 关键词：FRAILTY ALBUMIN INSULIN-LIKE Growth Factor-1 POLYPHARMACY

Effects of Bifidobacterium infantis on cytokine-induced neutrophil chemoattractant and insulin-like growth factor-1 in the ileum of rats with endotoxin injury被引量：7: 《World Journal of Gastroenterology》2019年第23期2924-2934,共11页Wei Wang Mei Sun Yu-Ling Zheng Liu-Yu Sun Shu-Qiang Qu; Supported by the Education Department of Heilongjiang Province,China,No.11521124; BACKGROUND The digestive tract is the maximal immunizing tissue in the body, and mucosal integrity and functional status of the gut is very important to maintain a healthy organism. Severe infection is one of the most...; 关键词：BIFIDOBACTERIUM ILEUM Cytokine-induced neutrophil CHEMOATTRACTANT INSULIN-LIKE growth factor-1 RATS

Alteration of oncogenic IGF-II gene methylation status associates with hepatocyte malignant transformation被引量：6: 《Hepatobiliary & Pancreatic Diseases International》2019年第2期158-163,共6页Bo-Jun Tai Min Yao Wen-Jie Zheng Yu-Cheng Shen Li Wang Jian-Ying Sun Meng-Na Wu Zhi-Zhen Dong Deng-Fu Yao; supported partly by grants from the National Natural Science Foundation(81673241,81702419,81872738,81873915);the Jiangsu Medical Science(BE2016698)&Graduate Innovation(KYCX17_1934);the International S.&T.Coopera-tion Program(2013DFA32150)of China; Background: Oncogenic insulin-like growth factor-II(IGF-II) is overexpressed in hepatocellular carcinoma(HCC). The present study aimed to analyze the dynamic alteration of IGF-II CpG site methylation status and its mo...; 关键词：Hepatocellular carcinoma INSULIN-LIKE growth factor-Ⅱ HYPOMETHYLATION Methylation-specific PCR Promoter Molecular mechanism

Specific activation of mGlu2 induced IGF-1R transactivation in vitro through FAK phosphorylation: 《Acta Pharmacologica Sinica》2019年第4期460-467,共8页Yong-jian Hu Qian Sun Wen-hua Zhang Yu-jia Huo Chan-juan Xu Jian-feng Liu; National Natural Science Foundation of China (NSFC grant nos. 31420103909, 31711530146, 31511130131);the Program of Introducing Talents of Discipline to the Universities of the Ministry of Education (grant no. B08029), Natural Science Foundation of.; Metabotropic glutamate receptor 2 (mGlu2) belongs to the group-ll metabotropic glutamate (mGlu) receptors and is a neurotransmitter G protein-coupled receptor. The group-ll mGlu receptors are promising antipsychotic t...; 关键词：METABOTROPIC glutamate RECEPTOR 2 INSULIN-LIKE growth factor 1 RECEPTOR TRANSACTIVATION FAK ERK1/2 LY379268 LY487379 mouse cortical neurons

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