Clévio Nóbrega’s laboratory is funded by the Cure CSB project;the Viljem Julijan Association for Children with Rare Diseases(Slovenia);the Algarve Biomedical Center Research Institute(ABC-Ri);funded by CRESC Algarve 2020(Operation Code:ALG-01-0145-FEDER-072586)(to CN)。
With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether th...
supported by the Haihe Laboratory of Cell Ecosystem Innovation Foundation,No.22HHXBSS00047(to PL);Graduate Science and Technology Innovation Project of Tianjin,No.2022BKY173(to LZ);Tianjin Municipal Science and Technology Bureau Foundation,No.20201194(to PL).
With the rapidly aging human population,age-related cognitive decline and dementia are becoming increasingly prevalent worldwide.Aging is considered the main risk factor for cognitive decline and acts through alterati...
Background: Aging-induced cardiac hypertrophy and reduced skeletal muscle strength contribute to increased disease risk and life burden in the elderly. FNDC5 acts as a protective muscle factor in both cardiac and skel...
In this article,we discuss Ye et al's recent article on the association between age at diabetes diagnosis and subsequent risk of age-related ocular diseases.The study,which utilized United Kingdom Biobank data,highlig...
supported by the National Key R&D Program of China (No.2019YFA0111900);the National Natural Science Foundation of China (No.82072506,92268115,82071970,81971775);the Science Fund for Distinguished Young Scholars of Hubei Province (No.2023AFA109);the Science and Technology Innovation Program of Hunan Province (No.2021RC3025);the Independent Exploration and Innovation Project for Postgraduate Students of Central South University (China) (No.2022ZZTS0268);Hunan Provincial Innovation Foundation for Postgraduate (No.CX20220350);the Science and Technology Project of Jianghan University (No.2022SXZX25);the Science and Technology Innovation Project of Jianghan University (China) (No.2021kjzx008).
The NRF2 pathway is a metabolic-and redox-sensitive signaling axis in which the transcription factor controls the expression of a multitude of genes that enable cells to survive environmental stressors,such as oxidati...
In recent years,advancements in nanomaterial production have significantly enhanced the efficiency of electrochemical sensors,facilitating rapid and accurate analysis of specific analytes.Electrochemical sensors have ...
grants from the Natural Science Foundation of Zhejiang Province(LQ21H250001);the National Natural Science Foundation of China(82322022 and 82001460).
Immunosenescence refers to the multifaceted and profound alterations in the immune system brought about by aging,exerting complex influences on the pathophysiological processes of diseases that manifest upon it.Using ...
Despite modern medicine’s advancements,age-related neurological diseases like Alzheimer’s disease and Parkinson’s disease remain challenging due to high costs,side effects,and limited accessibility.Ayurveda,a tradi...
supported by grants from the National Key R&D Program of China(2021YFC2400403);the National Natural Science Foundation of China(82201017,51972005);the Young Elite Scientist Sponsorship Program by CAST(2022QNRC001);the China Postdoctoral Science Foundation(2022M710257).
Compared with teenage patients,adult patients generally show a slower rate of tooth movement and more pronounced alveolar bone loss during orthodontic treatment,indicating the maladaptation of alveolar bone homeostasi...
Prostate cancer(PCa)is considered as an age-related disease and accounts for the most prevalence of urinary malignancies in men.1 We previously analyzed the cellular landscape of tumor microenvironment in PCa patients...