METABOTROPIC

作品数：9被引量：25H指数：3
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相关领域：医药卫生更多>>
相关作者：朱萍更多>>
相关机构：首都医科大学更多>>
相关期刊：《Chinese Journal of Traumatology》《Acta Pharmacologica Sinica》《Neural Regeneration Research》《Journal of Biomedical Science and Engineering》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划宁波市自然科学基金更多>>
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Glutamate receptors and glutamatergic signalling in the peripheral nerves被引量：4
《Neural Regeneration Research》2020年第3期438-447,共10页Ting-Jiun Chen Maria Kukley 
the laboratory of Maria Kukley was supported by the Excellence Strategy Program of the University of Tübingen(Deutsche Forschungsgemeinschaft,ZUK63)
In the peripheral nervous system,the vast majority of axons are accommodated within the fibre bundles that constitute the peripheral nerves.Axons within the nerves are in close contact with myelinating glia,the Schwan...
关键词：AMPA RECEPTORS axons GLUTAMATE METABOTROPIC GLUTAMATE RECEPTORS MYELINATION nerve injury NMDA RECEPTORS peripheral nervous system PNS Schwann cells synaptic SIGNALLING 
Specific activation of mGlu2 induced IGF-1R transactivation in vitro through FAK phosphorylation
《Acta Pharmacologica Sinica》2019年第4期460-467,共8页Yong-jian Hu Qian Sun Wen-hua Zhang Yu-jia Huo Chan-juan Xu Jian-feng Liu 
National Natural Science Foundation of China (NSFC grant nos. 31420103909, 31711530146, 31511130131);the Program of Introducing Talents of Discipline to the Universities of the Ministry of Education (grant no. B08029), Natural Science Foundation of.
Metabotropic glutamate receptor 2 (mGlu2) belongs to the group-ll metabotropic glutamate (mGlu) receptors and is a neurotransmitter G protein-coupled receptor. The group-ll mGlu receptors are promising antipsychotic t...
关键词：METABOTROPIC glutamate RECEPTOR 2 INSULIN-LIKE growth factor 1 RECEPTOR TRANSACTIVATION FAK ERK1/2 LY379268 LY487379 mouse cortical neurons 
Role of prefrontal cortex-nucleus accumbens glutamatergic projection in heroin reward and motivation
《中国药理学与毒理学杂志》2018年第9期725-726,共2页ZHU Hua-qiang LAI Miao-jun XU Wen-jin ZHUANG Ding-ding FU Dan HONG Qing-xiao LIU Hui-fen ZHOU Wen-hua 
National Basic Research Program of China(2015CB553504);National Natural Science Foundationof China (81471350;81671321);Natural Science Foundation of Ningbo Municipality,Zhejiang Province, China (2017A610214).
OBJECTIVE Glutamatergic projections from prefrontal cortex(PFc) to nucleus accumbens(NAc) regulate the dopamine(DA) release in NAc.However,it is not clear whether this circuit is effective for the reward and motivatio...
关键词：HEROIN ventromedial prefrontal cortex nucleus ACCUMBENS METABOTROPIC glutamatereceptor 2/3 REWARD MOTIVATION 
IL-10 Gene Knockout Reduces the Expression of mGlu Receptor 1a/b and Decreases the Glutamate-Dependent Production of Nitric Oxide被引量：1
《Journal of Biomedical Science and Engineering》2014年第13期1019-1029,共11页Sopiko Koriauli Tamar Barbakadze Nino Natsvlishvili Nino Dabrundashvili Eka Kvaratskhelia David Mikeladze 
IL-10 provides trophic and survival effects directly on neurons, promotes axonal outgrowth, and stimulates neuroregeneration. In this study, we analyzed the activities of arginase and nitric oxide synthase (NOS) in sy...
关键词：IL-10 POLYAMINE Biosynthesis NITRIC Oxide METABOTROPIC GLUTAMATE RECEPTOR 
Differential Expression of mGluR2 in the Developing Cerebral Cortex of the Mouse
《Journal of Biomedical Science and Engineering》2014年第13期1030-1037,共8页Pooja S. Venkatadri Charles C. Lee 
Glutamatergic synaptic transmission is an essential component of neural circuits in the central nervous system. Glutamate exerts its effects by binding to various types of glutamate receptors, which are found distribu...
关键词：METABOTROPIC GLUTAMATE RECEPTOR MOUSE CORTEX mGluR2 Group II MGLUR 
Effect of catgut implantation at acupoints on GABA_B and mGluR1 expressions in brain stem of rats with spasticity after stroke被引量：13
《Journal of Traditional Chinese Medicine》2014年第5期566-571,共6页Chengmei Liu Ruiqing Li Xiaolei Song Xiaodong Feng 
Supported by Henan University of Traditional Chinese Medcine Innovation Team Projet(No.2011XCXTD05)
OBJECTIVE: To investigate the effect of catgut implantation at acupoints on the expressions of γ-amino butyric acid B receptor(GABAB ) and metabotropic glutamate receptor 1(mGluR1) in the brain stem of rats with spas...
关键词：STROKE Muscle spasticity Embeddingtherapy Point GV 14 （Dazhui） Point CV 4 （Guanyu-an）  Point CV 12 （Zhongwan）  Metabotropic gluta-mate receptor type 1 
Changes of metabotropic glutamate receptor subtype 1a in diffuse brain injury with secondary brain insults and the effects of 2-methyl-4-carboxyphenylglycine被引量：3
《Chinese Journal of Traumatology》2003年第5期270-274,共5页费舟 章翔 刘恩渝 
NSFC (30 2 70 5 34);FoundationforUniversityKeyTeacherbytheMinistryofEducation
Objective: To observe the changes of metabotropic glutamate receptor 1a in rat brain in a rodent model of diffuse head injury with secondary insults and the effects of 2 methyl 4 carboxyphenylglycine (MCPG). Methods: ...
关键词：Brain injuries Receptors  metabotropic glutamata 
Genomic structure of metabotropic glutamate receptor 7 and comparison of genomic structures of extracellular domains of mGluR family被引量：4
《Chinese Science Bulletin》2002年第16期1330-1336,共7页Qingfa Wu Wei Dong Xiaohua Qi Weidong Bao Yuxin Niu Yiling Zhang Haiqing Zhang Chong Chen Bin Liu Songnian Hu et al. 
This work was supported by the "863" Program of the MOSC (Grant No. 863-J19) ;the Creative Program of the Chinese Academy of Sciences (Grant No. KSCX1-D4).
Metabotropic glutamate receptor 7, coupled with a chemical neurotransmitter L-glutamate, plays an important role in the development of many psychiatric and neurological disorders. To study the biological and genetic m...
关键词：METABOTROPIC GLUTAMATE receptor physical map genome EXON INTRON EXTRACELLULAR domain. 
Dynamic changes of mG1uR1 mRNA expression in rat hippocampus during seizures induced by kainic acid
《Journal of Medical Colleges of PLA(China)》2000年第1期55-59,共5页江文 黄远桂 高华 肖华胜 
Objective: To investigate temporospatial changes of mG1uR1 mRNA expression in rat hippocampus during seizures induced by kainic acid. Methods: Using in situ hybridization with Dig-labeled cDNA probes to examine mG1uR1...
关键词：EPILEPSY METABOTROPIC GLUTAMATE RECEPTORS HIPPOCAMPUS kainic acid ELECTROENCEPHALOGRAM 
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