POLYAMINE

作品数：110被引量：293H指数：12
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相关机构：中国医科大学南京农业大学河南农业大学周口师范学院更多>>
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Rational engineering of homospermidine synthase for enhanced catalytic efficiency toward spermidine synthesis
《Synthetic and Systems Biotechnology》2024年第3期549-557,共9页Wenjing Liu Xiaoxiang Hu Yi Yan Yujie Cai 
Spermidine is a naturally occurring polyamine widely utilized in the prevention and treatment of various diseases.Current spermidine biosynthetic methods have problems such as low efficiency and complex multi-enzyme c...
关键词：Homospermidine synthase POLYAMINE Site-directed mutagenesis SPERMIDINE Structural analysis 
Bioinspired super-hydrophilic zwitterionic polymer armor combats thrombosis and infection of vascular catheters
《Bioactive Materials》2024年第7期493-504,共12页You Ke Haotian Meng Zeyu Du Wentai Zhang Qing Ma Yuting Huang Linxian Cui Yifeng Lei Zhilu Yang 
supported by the National Natural Science Foundation of China (Project 82072072,32261160372,32171326,32371377);the Guangdong Basic and Applied Basic Research Foundation (2022B1515130010,2021A1515111035);Dongguan Science and Technology of Social Development Program (20231800906311,20231800900332).
Thrombosis and infection are two major complications associated with central venous catheters(CVCs),which significantly contribute to morbidity and mortality.Antifouling coating strategies currently represent an effic...
关键词：ANTI-INFECTION ANTITHROMBOSIS Phenol-polyamine SUPER-HYDROPHILICITY Zwitterionic polymers 
A PET probe targeting polyamine transport system for precise tumor diagnosis and therapy
《Asian Journal of Pharmaceutical Sciences》2024年第3期146-159,共14页Ming Zhou Xiaoqin Yin Bei Chen Shuo Hu Wenhu Zhou 
supported by the Science and Technology Innovation Team Talent Project of Hunan Province(No.2021RC4056);the clinical research foundation of the National Clinical Research Center for Geriatric Diseases(XIANGYA)(No.2020LNJJ01);the Natural Science Foundation of Hunan Province in China(No.2021JJ20084);the Science and Technology Innovation Program of Hunan Province(No.2021RC3020)。
Polyamine metabolism dysregulation is a hallmark of many cancers,offering a promising avenue for early tumor theranostics.This study presents the development of a nuclear probe derived from spermidine(SPM)for dual-pur...
关键词：PET imaging Polyamine metabolism SPERMINE RADIOPHARMACEUTICAL MELANOMA 
Possible Role of Cellular Polyamine Metabolism in Neuronal Apoptosis
《Current Medical Science》2024年第2期281-290,共10页Xin-tong JI Wen-lei YU Meng-jia JIN Lin-jie LU Hong-ping YIN Huan-huan WANG 
supported by grants from Zhejiang Provincial Natural Science Foundation of China(No.LY19H260003);Zhejiang Medical Health Science and Technology Project of China(No.2024KY1661).
Recent studies have shown that cellular levels of polyamines(PAs)are significantly altered in neurodegenerative diseases.Evidence from in vivo animal and in vitro cell experiments suggests that the cellular levels of ...
关键词：POLYAMINE APOPTOSIS MITOCHONDRIA neurodegenerative disease 
An insect sclerotization-inspired antifouling armor on biomedical devices combats thrombosis and embedding被引量：1
《Bioactive Materials》2024年第3期562-571,共10页Nan Lyu Daihua Deng Yuting Xiang Zeyu Du Xiaohui Mou Qing Ma Nan Huang Jing Lu Xin Li Zhilu Yang Wentai Zhang 
supported by the National Natural Science Foundation of China,China(Project 82202325,82072072,32171326,32261160372);the Guangdong Basic and Applied Basic Research Foundation,China(2022B1515130010,2021A1515111035);Dongguan Science and Technology of Social Development Program,China(20231800906311,20231800900332);China Postdoctoral Science Foundation,China(2022M721524);Leading Talent Project of Guangzhou Development District,China(2020-L013)。
Thrombus formation and tissue embedding significantly impair the clinical efficacy and retrievability of temporary interventional medical devices.Herein,we report an insect sclerotization-inspired antifouling armor fo...
关键词：ANTIFOULING Temporary interventional devices Insect sclerotization Phenol-polyamine chemistry Universal armor 
Synthesis of a High-Efficiency Demulsifier and Study on Optimal Demulsification Conditions
《China Petroleum Processing & Petrochemical Technology》2024年第1期107-115,共9页Zhu Shuai Zhang YingYu Gui Xia 
supported by National Natural Science Foundation of China(NSFC 21676145);Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD,China).
Oil and water separation has always been a top priority in the oil industry.In this study,a series of hyperbranched fluorinated polyamine-amine polymers(HFPA1-5)were synthesized directly using an improved“one-pot met...
关键词：HYPERBRANCHED fluorinated polyamine-amine nano-SiO_(2) 
Unmasking metabolic dependencies in pancreatic cancer: aberrant polyamine synthesis as a promising new therapeutic target
《Signal Transduction and Targeted Therapy》2023年第11期5151-5152,共2页Gerrit Wolters-Eisfeld Thilo Hackert Cenap Güngör 
In a recently published Nature article,Lee et al.investigated distinct metabolic dependencies of pancreatic ductal adenocarcinoma(PDA)cells compared to normal tissue,and discovered that PDA cells exhibited a unique re...
关键词：SYNTHESIS DEN depen 
Analysis of a Strong-Inhibition Polyamine Drilling Fluid
《Fluid Dynamics & Materials Processing》2023年第9期2431-2447,共17页Yu Fan Jianhua Guo Xihui Hu Rui Wang Weiqiang Xu 
Drilling technologies based on oil-based drillingfluids and strong inhibitory saltwaterfluids are affected by draw-backs such as downhole accidents where sticking and wellbore instabilities occur.Existing polyamine dril...
关键词：High performance POLYAMINE strong inhibition adhesion sticking wellbore stability 
Germplasm Resources,Genes and Perspective for Aromatic Rice被引量：3
《Rice science》2023年第4期294-305,共12页Prafulla Kumar BEHERA Debabrata PANDA 
University Grant Commission, New Delhi, India for providing Non-National Eligibility Test fellowship
Aromatic rice is considered an important commodity in the global market because of its strong aroma and eating and cooking quality.Asian countries,such as India and Pakistan,are the leading traders of Basmati rice,whe...
关键词：aromatic rice 2-acetyl-1-pyrroline polyamine degradation pathway quality trait 
Dietary supplementation with 0.4%L-arginine between days 14 and 30 of gestation enhances NO and polyamine syntheses and water transport in porcine placentae
《Journal of Animal Science and Biotechnology》2023年第2期627-639,共13页Cassandra M.Herring Fuller W.Bazer Gregory A.Johnson Heewon Seo Shengdi Hu Mohammed Elmetwally Wenliang He Daniel B.Long Guoyao Wu 
supported by Agriculture and Food Research Initiative Competitive Grant no.2014–05142 from the USDA National Institute of Food and Agriculture.
Background:Most embryonic loss in pigs occurs before d 30 of gestation.Dietary supplementation with L-arginine(Arg) during early gestation can enhance the survival and development of conceptuses(embryo/fetus and its e...
关键词：Angiogenesis ARGININE FETUS PLACENTA Reproduction 
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