ANTHRAQUINONES

作品数：35被引量：109H指数：6
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相关领域：医药卫生理学更多>>
相关作者：吴子斌王峥涛徐珞珊卢艳花屠鹏飞更多>>
相关机构：香港中文大学中国药科大学北京大学河南师范大学更多>>
相关期刊：《Chinese Herbal Medicines》《Chinese Journal of Integrative Medicine》《Chinese Journal of Natural Medicines》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金国家科技支撑计划俄罗斯基础研究基金更多>>
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The haplotype-resolved genome assembly of autotetraploid rhubarb Rheum officinale provides insights into its genome evolution and massive accumulation of anthraquinones被引量：1
《Plant Communications》2024年第1期196-214,共19页Hongyu Zhang Qiang He Longsheng Xing Ruyu Wang Yu Wang Yu Liu Qinghong Zhou Xuanzhao Li Zheng Jia Ze Liu Yuqing Miao Tao Lin Wei Li Huilong Du 
supported by the Natural Science Foundation of Hebei Province (grant C2021201048);the National Natural Science Foundation of China (grant 32100500);the Young Elite Scientists Sponsorship Program by CAST grant YESS20210080.
Rheum officinale,a member of the Polygonaceae family,is an important medicinal plant that is widely used in traditional Chinese medicine.Here,we report a 7.68-Gb chromosome-scale assembly of R.officinale with a contig...
关键词：Rheum officinale genomics comparative genomics POLYPLOID anthraquinone biosynthesis 
Identification of the multiple bioactive derivatives and their endogenous molecular targets that may mediate the laxative effect of rhubarb in rats
《Journal of Traditional Chinese Medical Sciences》2020年第2期210-220,共11页Lei Xie Ying Wang Gan Luo Wenjuan Zhou Jiayan Miao Siqi Tang Qin Jiang Yage Guan Xiaoyan Gao 
the National Natural Science Foundation of China(81673562 and 81973467);the Fundamental Research Funds for the Central Universities of China(2020-JYB-ZDGG-033).
Objective:To determine the mechanism of the laxative effect of rhubarb(Rheum tanguticum Maxim.ex Balf.)in rats using a combined bioinformatic and in vivo approach.Methods:Substances derived from rhubarb that are prese...
关键词：RHUBARB LAXATIVE ANTHRAQUINONES Anthrones C-KIT AQUAPORIN-3 
Simultaneous Determination of 10 Anthraquinones in Rhubarb Based on HPLC-Q-HR/MS被引量：4
《Chinese Herbal Medicines》2017年第4期388-395,共8页Su-xiang Feng Meng-meng Li Di Zhao Xian-he Li Lei Zhang Zhe Wang Ning-ning Gao 
National Natural Science Foundation of China(No.81274179)
Objective To develop a simple, sensitive, and precise method for simultaneous determination of 10 anthraquinones in Rhubarb. Methods HPLC-Q-HR/MS was employed for simultaneous quantification of free anthraquinones（al...
关键词：Anthraquinones HPLC-Q-HR/MS quality control quantitative analysis Rhubarb 
Bidirectional solid fermentation using Trametes robiniophila Murr. For enhancing efficacy and reducing toxicity of rhubarb (Rheum palmatum L.)被引量：5
《Journal of Traditional Chinese Medical Sciences》2017年第3期306-313,共8页Yancong Zhang Li Zhou Weiwei Ma Xiaosa Shi Hongmei Zhang Xinyuan Shi 
Objective:To investigate the potential of bidirectional solid fermentation of rhubarb (Rheum palmatum L.) for reducing its toxicity and enhancing its medicinal efficacy.Methods:The fungus Trametes robiniophila Murr.wa...
关键词：RHUBARB TRAMETES robiniophila Murr. BIDIRECTIONAL solid FERMENTATION ANTHRAQUINONES Cancer inhibition 
Distribution and pharmacokinetics of five Rhubarb anthraquinones in rabbits and rats被引量：2
《Journal of Chinese Pharmaceutical Sciences》2017年第2期115-123,共9页Ting Cui Qixin Zhou Dan Zhang Xinhui Jiang 
The Research Fund of Chongqing Science&Technology Commission(Grant No.cstc2013jcyj A10040);Research Start-up Fund of Pharmacy School of Chongqing Medical University
The main active components of Rhubarb are anthraquinones（AQs）, most of which are glycosides and others are free. The concentrations of AQs derivatives（rhein, aloe-emodin, emodin, chrysophanol and physcion） in plas...
关键词：RHUBARB ANTHRAQUINONES PHARMACOKINETICS DISTRIBUTION 
A Strategy for Detecting Absorbed Bioactive Compounds for Quality Control in the Water Extract of Rhubarb by Ultra Performance Liquid Chromatography with Photodiode Array Detector被引量：4
《Chinese Journal of Integrative Medicine》2012年第9期690-698,共9页王杨 黄熙 梁清华 范荣 秦锋 呙勇 闫奎坡 刘维 罗杰坤 李云辉 毛喜莲 刘昭前 周宏灏 
Supported by the Fund for Key Labo ratory of Traditional Chinese Medicine Gan of State Administration of Traditional Chinese Medicine;the Major Research Plan of the National Natural Science Foundation of China(No.90409010);was partly supported by the Huge Project to Boost Chinese Drug Development(No.2009ZX09304-003)
Objective： To detect absorbed bioactive compounds of the water extract whose pharmacodynamic effect was craniocerebral protection for quality control assessment. Methods： Anthraquinones in water extract of rhubarb ...
关键词：quality control absorbed bioactive compounds RHUBARB ultra performance liquid chromatography craniocerebral injury ANTHRAQUINONES 
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