MACROLIDE

作品数：32被引量：76H指数：4
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相关领域：医药卫生理学更多>>
相关作者：夏曦李少丽李建成丁双阳江海洋更多>>
相关机构：中国农业大学首都儿科研究所中国科学院更多>>
相关期刊：《Acta Pharmacologica Sinica》《Chinese Medical Journal》《Advances in Microbiology》《World Journal of Pediatrics》更多>>
相关基金：国家自然科学基金北京市自然科学基金“十一五”国家科技支撑计划The Royal Society更多>>
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Synthesis of novel 15-membered macrolide dimers
《Chinese Chemical Letters》2009年第8期931-934,共4页Shu Tao Ma Rui Xin Ma Rui Qing Xian Bo Jiao 
supported by the National Natural Science Foundation of China(No.2087208 1);Natural Science Foundation of Shandong(No.Y2006C3 1);Shandong Science and Technology Promotion Project(No.2005GG3202098).
A series of novel dimers of 15-membered macrolides was synthesized and evaluated. The dimers exhibited excellent activity against erythromycin-susceptible S. pneumonia, but did not show any improved activity against e...
关键词：MACROLIDE Azithromycin derivatives D/mers SYNTHESIS 
Synthesis of novel 15-membered macrolide derivatives被引量：2
《Chinese Chemical Letters》2008年第4期409-411,共3页Rui Qing Xian Shu Tao Ma Bo Jiao 
supported by NNSFC(No.20372043),Shandong Science and Technology Promotion Project(No.2005GG3202098);Natural Science Foundation of Shandong Province(No.Y2006C31).
In order to develop new antibiotics effective against resistant bacteria,a series of novel 15-membered macrolide derivatives were designed and synthesized by the modification of hydroxyl groups at C-11,C-12 and C-4＂ ...
关键词：MACROLIDE Azithromycin derivatives SYNTHESIS 4＂-Carbamate derivatives 
Synthesis of derivatives of imidazo[4,5-b]pyridine:Novel sulfur contained side chains for macrolide antibiotics被引量：2
《Chinese Chemical Letters》2008年第1期1-4,共4页Lu Liu Peng Xu Liang Zhou Ping Sheng Lei 
Finacial support of this research by the National Natural Science Foundation of China （No. 30572275） ；Natural Science Foundation of Beijing （No. 7062047） are gratefully acknowledged by the authors.
Two series of novel derivatives of imidazo[4,5-b]pyridine were synthesized. These compounds could be used as side chains of semisynthesised ketolide antibiotics. The side chains have free amine group which can attache...
关键词：MACROLIDE Heterarylalkyl sulfur contained side chain Imidazo[4 5-b]pyridine Synthesis HMBC 
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