This work was financially supported by National Natural Science Foundation of China(Grant Nos:31772242,31972348,and 31672092).
Dramatic decrease of sugar uptake is a general phenomenon in Streptomyces at stationary phase,when antibiotics are extensively produced.Milbemycins produced by Streptomyces bingchenggensis are a group of valuable macr...
supported by the National Natural Science Foundation of China(No.2087208 1);Natural Science Foundation of Shandong(No.Y2006C3 1);Shandong Science and Technology Promotion Project(No.2005GG3202098).
A series of novel dimers of 15-membered macrolides was synthesized and evaluated. The dimers exhibited excellent activity against erythromycin-susceptible S. pneumonia, but did not show any improved activity against e...
Supported by the National Natural Science Foundation of China (No. 30300296).
To investigate the prevalence of resistance to macrolide, lincosamide and streptogramin B (MLSs) antibiotics in Staphylococcus epiderrnidis caused nosocomial infection in the Chinese multicenter hospital, we tested ...