云南高校图书馆联盟文献共享服务平台- CONUS

CONUS: 作品数：26被引量：53H指数：4; 导出分析报告; 相关领域：生物学医药卫生更多>>; 相关作者：周晓薇戴秋云刘凤云黄培堂李晓玲更多>>; 相关机构：军事医学科学院汕头市中心医院汕头大学复旦大学更多>>; 相关期刊：《World Journal of Clinical Cases》《Science Bulletin》《Agricultural Biotechnology》《生态学报》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家高技术研究发展计划更多>>

Isolation and characterization of five novel mini-M conotoxins from the venom of mollusk-hunter snail Conus bandanus: 《Asian Pacific Journal of Tropical Biomedicine》2020年第8期343-352,共10页Nguyen Bao Jean-Pière LE CAER Phan Thi Khanh Vinh; funded by Vietnam National Foundation for Science and Technology Development(NAFOSTED)under grant number 106-NN.02-2015.14; Objective:To determine the new M-superfamily conotoxins from molluscivorous snail Conus bandanus in Vietnam.Methods:Conus bandanus venom was fractionated and purified on HPLC system with an analytical reversed-phase C...; 关键词：Mini-M conotoxin Conus bandanus Cone snail venom

A perspective on toxicology of Conus venom peptides: 《Asian Pacific Journal of Tropical Medicine》2015年第5期337-351,共15页Palanisamy Satheesh Kumar Dhanabalan Senthil Kumar Sundaresan Umamaheswari; The evolutionarily unique and ecologically diverse family Conidae presents fundamental opportunities for marine pharmacology research and drug discovery.The focus of this investigation is to summarize the worldwide di...; 关键词：Distribution CONUS CONOTOXIN Peptide TOXICOLOGY PHARMACOLOGY

Chemical synthesis and characterization of two α4/7-conotoxins被引量：2: 《Acta Biochimica et Biophysica Sinica》2010年第10期745-753,共9页Can Peng Weihua Chen Tanya Sanders Geoffrey Chew Jing Liu Edward Hawrot Chengwu Chi; α-Conotoxins are small disulfide-constrained peptides that act as potent and selective antagonists on specific subtypes of nicotinic acetylcholine receptors （nAChRs）. We previously cloned two α-conotoxins, Mrl.1 f...; 关键词：CONUS α4/7-conotoxin nicotinic acetylcholinereceptor ANALGESIC

Characterization of a novel α4/4-conotoxin, Qcl.2, from vermivorous Conus quercinus被引量：1: 《Acta Biochimica et Biophysica Sinica》2009年第10期858-864,共7页Can Peng Weihua Chen Yuhong Han Tanya Sanders Geoffrey Chew Jing Liu Edward Hawrot Chengwu Chi Chunguang Wang; As part of continuing studies of the identification of gene organization and cloning of novel α-conotoxins, the first α4/4-conotoxin identified in a vermivorous Conus species, designated Qcl.2, was originally obta...; 关键词：nicotinic acetylcholine receptor subtype α4/4-conotoxin post-translational modification Xenopus oocyte

mrle, a conotoxin from Conus marmoreus with a novel disulfide pattern被引量：5: 《Acta Biochimica et Biophysica Sinica》2008年第5期391-396,共6页Yanfang Wang Xiaoxia Shao Min Li Sumin Wang Chengwu Chi Chunguang Wang; Conotoxins are well known for their highly variable structures and functions. Here we report the identification of a novel conotoxin named mrle from Conus marmoreus. mrle is composed of 11 amino acid residues cross-li...; 关键词：CONOTOXIN Conus marmoreus disulfide connectivity mrle

Two Potent α3/5 Conotoxins from Piscivorous Conus achatinus被引量：5: 《Acta Biochimica et Biophysica Sinica》2007年第6期438-444,共7页Li LIU Geoffrey CHEW Edward HAWROT Chengwu CHI Chunguang WANG; Every cone snail produces a mixture of different conotoxins and secretes them to immobilize their prey and predators, α3/5 Conotoxins, isolated from fish-hunting cone snails, target muscle nicotinic acetylcholine rec...; 关键词：cone snail α3/5 conotoxin disulfide bond nicotinic acetylcholine receptor

cDNA Cloning of Two Novel T-superfamily Conotoxins from Conus leopardus: 《Acta Biochimica et Biophysica Sinica》2006年第4期287-291,共5页Wei-Hua CHEN Yu-Hong HAN Qi WANG Xiao-Wei MIAO Ling OU Xiao-Xia SHAO; This work was supported by a grant from the National Natural Science Foundation of China (No.30170210); The full-length cDNAs of two novel T-superfamily conotoxins, Lp5.1 and Lp5.2, were cloned from a vermivorous cone snail Conus leopardus using 3＇/5＇-rapid amplification of cDNA ends. The cDNA of Lp5.1 encodes a precu...; 关键词：Conus leopardus T-superfamily CONOTOXIN cDNA cloning

Conus Peptides-A Rich Pharmaceutical Treasure被引量：8: 《Acta Biochimica et Biophysica Sinica》2004年第11期713-723,共11页Cheng-Zhong WANG and Cheng-Wu CHIInstitute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences, the Chinese Academy of Sciences, Shanghai 200031, China Institute of Neuroscience, the Chinese Academy of Sciences, Shanghai 200031, China Institute of Protein Research, Tongji University, Shanghai 200092, China; Marine predatory cone snails (genus Conus) with over 500 species represent what is arguably the largest single genus of marine animals alive today. All Conus are venomous and utilize a complex mixture of Conus peptide...; 关键词：Conus peptide CONOTOXIN neuropathic disorder pharmaceutical potency

一种新型织绵芋螺毒素可增强神经元钙电流: 《分析测试学报》2004年第z1期1-2,共2页刘凤云李晓玲周晓薇戴秋云黄培堂; 　　从中国南海织绵芋螺中分离出生物活性强、电生理效应特异的新的芋螺毒素.通过毒素分离纯化,并经生物活性测定,氨基酸测序,电生理效应等研究.分离到1种新的织绵芋螺毒素Tx7,它是由27个氨基酸组成.其序列为GCSSVCNSHTDCVTHCICTFRGCGA...; 关键词：Conus textile CONOTOXIN ISOLATION PURIFICATION

New O-superfamily conotoxins from Conus striatus inhabited near Chinese Hainan Island: 《Chinese Science Bulletin》2000年第5期432-435,共4页Baisong Lu Fang Yu Jianhua Wang Siqing Zhao Dong Zhao Qiuyun Dai Peitang Huang Cuifen Huang; Conotoxins are short peptide-toxins with specific targets and large diversity. They are usetul in analgesia, neuroprotection, detection of some kinds of deseases, and receptor and ion channel study. in order to explor...; 关键词：CONOTOXIN RACE CONOPEPTIDE CONUS striatus O-superfamily conotoxin.

CONUS