supported by the European Union Horizon 2020 Research and Innovation Programme(Marie Skłodowska-Curie grant agreement No 847419);supported by the Biotechnology and Biological Sciences Research Council via a Discovery Fellowship(BB/W00934X/1);the Aston University RKE Pump Priming Programme;funded by UKRI’s Research England as part of their Expanding Excellence in England(E3)fund;supported by a UKRI Frontier Research Grant EP/Y023684/1(following assessment as an ERC Advanced grant,FORTIFY,ERC-2022-ADG-101096882 under the UK Government Guarantee scheme)and acknowledged a Biotechnology and Biological Sciences Research Council Pioneer Award(BB/Y512874/1).MMS was supported by a Medical Research Council Career Development Award(MR/W027119/1);acknowledged support from the BHF Centre of Research Excellence,University of Oxford(grant code:RE/24/130024);a Biotechnology and Biological Sciences Research Council Pioneer Award(BB/Y512874/1).
Glymphatic flow has been proposed to clear brain waste while we sleep.Cerebrospinal fluid moves from periarterial to perivenous spaces through the parenchyma,with subsequent cerebrospinal fluid drainage to dural lymph...
supported by the National Natural Science Foundation of China(82370591);Key Project of the Joint Fund of the National Natural Science Foundation of China(U21A20345);the Fundamental Research Funds for the Central Universities(WK9110000197);the Anhui Province Higher Education Science Research Project(Natural Science)(2023AH040078);the Horizontal Project(H2023031);the 2021 Academic Funding Project for Top Talents in Higher Education Discipline(Major)(gxbjZD2021048);the 2023 Hefei Natural Science Foundation Project(2023018);the 2023 Anhui Medical University Research Level Improvement Plan Project(2023xkiT010);Pharmaceutical Peak Discipline Talent Fund Project“Research oriented Young Talents”(2023xkkq3);Anhui Province Excellent Research and Innovation Team Project(2024AH010013);the Anhui Medical University International Students Innovation Training Program Project(GJY202305;S202410366120);the 2023 New Era Education Provincial Quality Engineering Project Graduate Joint Training Demonstration Base[2023lhpysfjd023];the Early Contact Research Projects(2022-ZQKY-80;2023-YXYZQKY-40).
Alcohol-associated liver disease(ALD)is a hepatocyte dysfunction disease caused by chronic or excessive alcohol consumption,which can lead to extensive hepatocyte necrosis and even liver failure.Currently,the pathogen...
This study investigates the application of carbon dioxide (CO2) sequestration to address challenges in water-drive gas reservoirs, specifically focusing on improving gas recovery and mitigating water invasion. Traditi...
supported by grants from the National Natural Science Foundation of China(32370309);the STI 2030-Major Projects(2023ZD040710X);the National Natural Science Foundation of China(31700223);Jiangsu Agricultural Science and Technology Innovation Fund(CX(23)1033);Jiangsu Collaborative Innovation Center for Modern Crop Production and Cyrus Tang Innovation Center for Crop Seed Industry。
Members of the cyclic nucleotide-gated channel(CNGC)proteins are reportedly involved in a variety of biotic and abiotic responses and stomatal movement.However,it is unknown if and how a single member could regulate m...
Following her disinfection routine,Liu Shuo,a Beijing-based pet sitter in her 20s,puts on shoe covers,enters the access code for the front door and initiates a video call with the pet owner to begin her work.At this h...
Biological Breeding of Stress Tolerant and High Yield Cotton Varieties(2023ZD04040)to L.M.;National Natural Science Fund of China for Distinguished Young Scholars(32325039);National Natural Science Foundation of China(32272128)to S.J.,the National Natural Science Foundation of China(32401780);Key Scientific and Technological Project of Henan Province(222102110151)to S.L.;Major Science and Technology Project of Xinjiang Uygur Autonomous Region(2023A02003-2)to B.L.
Calcium-dependent protein kinases(CDPKs)act as key signal transduction enzymes in plants,especially in response to diverse stresses,including herbivory.In this study,a comprehensive analysis of the CDPK gene family in...
supported by the National Natural Science Foundation of China,Nos.81672261(to XH),81972151(to HZ),82372568(to JL);the Natural Science Foundation of Guangdong Province,Nos.2019A1515011106(to HZ),2023A1515030080(to JL)。
Prolife ration of neural stem cells is crucial for promoting neuronal regeneration and repairing cerebral infarction damage.Transcranial magnetic stimulation(TMS)has recently emerged as a tool for inducing endogenous ...
supported in part by the National Nature Science Foundation(81874022 and 82172483 to Xinyu Liu,82102522 to Lianlei Wang,82072478 to Yunpeng Zhao,82072435 to Qiang Yang,82073437 to Weiwei Li,81930070 to Shiqing Feng,82272548 to Lei Cheng);Key R&D Project of Shandong Province(2022CXGC010503 to Xinyu Liu);Shandong Natural Science Foundation(ZR202102210113 to Lianlei Wang,ZR2020YQ54 to Yunpeng Zhao);Shandong Province Taishan Scholar Project(tsqn202211317 to Lianlei Wang).The authors thank the Translational Medicine Core Facility of Shandong University for the consultation and instrument availability that supported this work.
To date,several molecules have been found to facilitate iron influx,while the types of iron influx channels remain to be elucidated.Here,Piezo1 channel was identified as a key iron transporter in response to mechanica...
During an interview with Beijing Review,Zhou Zhanfeng,who had just seen off a board member from a prominent German automaker and his family,who had traveled to China,in Beijing,disclosed that the visitor had said the ...
financially supported by grants from the National Natural Science Foundation of China(82170873;81871095);the National Key R&D Program of China(2018YFC2000304);the Tsinghua University Spring Breeze Fund(20211080005).
Nonalcoholic fatty liver disease(NAFLD)is a high-incidence lipid disorder that affects more than a quarter of the population worldwide,and dietary intervention is the recognized treatment.Starch is the main component ...