Chiral cyclic amino alcohols with contiguous stereocenters are key building blocks in the synthesis of bioactive molecules and pharmaceuticals.Artificial cascade biocatalysis represents an attractive method for the sy...
Supported by the National Basic Research Program of China (Grant No. 2007CB925103);the National Natural Science Foundation of China (Grant No. 20602017);NCET-07-0425
Unprecedented synthesis of chiral (aza)crown ethers of calix[4]arene derivatives bearing a carboxyl amide bridge was described. The synthesis proceeds through condensation of the corresponding dinitriles with opticall...
Reductive cleavage of the NO bond of isoxazolidine ring with catalytic hydrogenation over Raney nickel was described. Bicyclic isoxazolidines could be effectively converted into the corresponding 1,3-amino-alcohol pos...
A series of 4-aryl-6-aryloxymethylmorpholin-3-one derivatives were synthesized very efficiently from readily available starting compounds in two steps. Ring opening reactions of epoxides with aniline compounds on alum...
Amino-1,1-diferrocenylethanol 2 was prepared by reduction of trimethylsilyl cyanohydrin ether of diferrocenyl ketone. The crystal structure of 2 was further defined by X-ray diffraction.