financially supported by the National Natural Science Foundation of China(Nos.21403154 and 22003045);the Natural Science Foundation of Tianjin(No.13JCYBJC38700);the Tianjin Municipal Education Commission(No.2018KJ137)。
Benzo[b]thiophene fused compounds with a unique active heterocyclic skeleton have wide applications in the fields of medicinal chemistry,organic synthesis,and organic functional materials,which resulted in rapid devel...
supported by the National Key Research and Development Program of China(2018YFA0209401);the National Natural Science Foundation of China(22171053,21733003);the Natural Science Foundation of Shanghai(21zR1409600)。
S-fused heterocycles have become popular building blocks to construct functional polycyclic compounds.In contrast to the abundant synthetic methodologies for thiophene-fused aromatics,the synthesis of S-heterocycles c...
Heteroatom-embedded buckybowl molecules provide a fundamental molecular framework that has potential applications in various research fields.However,selective introduction of heteroatoms into buckybowls is challenging...
the National Natural Science Foundation of China(Nos.U1604285,21772032 and 21702051);Program for Changjiang Scholars and Innovative Research Team in University(PCSIRT)of Ministry of Education of China(No.IRT1061);the 111 Project(No.D17007);Henan Provincial Natural Science Foundation(No.162300410180);Key Project of Henan Educational Committee(No.18A150009);Program for Innovative Research Team of Science and Technology in the University of Henan Province(No.18IRTSTHN004)。
We report a 2-iodoxybenzoic acid(IBX)-mediated intarmolecular oxidative spiro-fused tandem cyclization reaction of tryptophan analogs bearing an N-arylamides side-chain to rapidly afford polycyclic spiroindolines feat...
Generaus financial support was from the National NaturalScience Foundation of China(Nos.21702235,81841001);the Fundamental Research Funds for the Central Public Welfare Research Institutes(Nos.ZZ13-YQ-098,ZZ10-024,ZXKT17053);the Major National Science and Technology Program of China forlnnovative Drug(No.2017ZX09101002-001-001).
of main observation and conclusion Polycylic fused quinazolinones with anti-malarial activity were synthesized through tert-butyl hydro-peroxide(TBHP)-mediated oxidative decarboxylative cyclization between commercaly ...
the National Natural Science Foundation of China(Nos.21672176 and 21332007);the National Key R&D Program of China(grant No.2017YFA0207302);the Program for Changjiang Scholars and Innovative Research Team in University(PCSIRT)of Ministry of Education.
The efficient construction of functionalized polycyclic structures is an imports nt objective in organic synthesis.Herein,we disclose a three-step"[2+n]"annulation method for the transformation of cyclic ketones to fu...
The crystal structure of 1,7,8,9-tetrachloro-4-benzyl-10,10-dimethoxy-4-azatricyclo- (5,2,1,0^2,6)dec-8-ene-3,5-dione (C18H15Cl4NO4, Mr = 451. 11) has been determined by single-crystal X-ray diffraction analysis. ...
One of the present authors has put forword a quantitative relationship between structure and carcinogenic activity for polycyclic aromatic hydrocarbons (PAH), i.e.