supported by grants from the National Natural Science Foundation of China;the Key Research Program of the Chinese Academy of Sciences;the National Key Technology Support Program
Cyclophilin A(CypA,encoded by PPIA)is a peptidyl-prolyl cis/trans isomerase(PPIase)that is expressed ubiquitously in all type of cells.CypA is the major cellular target for the immunosuppressive drug cyclosporin A(CsA...
LepA, the highly conserved translational GTPase (trGTPase), triggers one-codon back-movement of the elongating ribosome. Here we identify a new enzymatic activity