DISINTEGRINS

作品数:4被引量:1H指数:1
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相关领域:医药卫生更多>>
相关作者:赵志慧张臻刘臻朱泽章钱邦平更多>>
相关机构:南京大学医学院附属鼓楼医院更多>>
相关期刊:《Journal of Chinese Pharmaceutical Sciences》《Science China Chemistry》《Advances in Breast Cancer Research》《Journal of Cancer Therapy》更多>>
相关基金:国家自然科学基金更多>>
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Bibliometric and visual analysis of global research on snake venom disintegrins(2009–2023)
《Journal of Chinese Pharmaceutical Sciences》2024年第11期1012-1024,共13页Yinxiang Lan Xiuliang Qiu Dandan Huang 
Startup Fund for Scientific Research,Fujian Medical University(Grant No.2022QH1216)。
Snake venom disintegrins,through their inhibition of integrin-related binding,effectively impede both cell-cell and cell-matrix interactions as well as signal transduction pathways,rendering them promising candidates ...
关键词:Snake venom disintegrins Biblimetric analysis CITESPACE VOSviewer Research trends 
Action of the Disintegrin Contortrostatin on Breast Cancer Cell Primary Cultures
《Advances in Breast Cancer Research》2013年第4期161-169,共9页Ifigeneia Marinou Sophia Havaki Nikos Goutas Dimitrios Vlachodimitropoulos Georgios Baltatzis Eumorphia G. Konstantakou Dimitrios J. Stravopodis Dimitrios G. Koudoumas Evangelos Marinos Mirsini Kouloukoussa 
Integrins mediate cell adhesion to the extracellular matrix (ECM). In particular, integrin alphavbeta3 recognizes the RGD motif as a ligand-binding site on various extracellular molecules of the extracellular matrix. ...
关键词:BREAST Cancer DISINTEGRINS Contortrostatin INTEGRIN Alphavbeta3 APOPTOSIS Primary CULTURES 
Deciphering structural and functional roles of disulfide bonds in decorsin被引量:1
《Science China Chemistry》2013年第10期1485-1492,共8页WU LingZhi LI Ying YANG Yang QIN Meng 
supported by the National Natural Science Foundation of China(91127026,11074115 and 61101056);the Open Project of State Key Laboratory of Bioelectronics of Southeast University(2011E14);supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions
Decorsin, an antagonist of integrin glycoprotein IIb/IIIa, contains Arg-Gly-Asp (RGD) sequence and three disulfide bridges. The function of RGD sequence has already been well defined, but the roles of conserved disu...
关键词:antihemostatic activity decorsin disulfide bonds DISINTEGRINS platelet aggregation inhibitor RGD-sequence 
Antitumor Activity of Disintegrin-Like Components from the Venom of <i>Montivipera</i><i>raddei</i>
《Journal of Cancer Therapy》2011年第5期752-759,共8页Silva Amiryan 
Our findings represent the first report of the antitumor activity of the disintegrin-like components from the venom of Armenian viper (M. raddei). The venom of M. raddei was separated by reverse phase high-performance...
关键词:Snake VENOM Montivipera raddei (Armenian Viper) DISINTEGRINS Antitumor Activity 
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