CAMPTOTHECINS

作品数:4被引量:5H指数:1
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相关期刊:《Cancer Biology & Medicine》《Chinese Chemical Letters》《Cancer Drug Resistance》更多>>
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Facile synthesis and cytotoxicity of 5-C-alkylates of 20(S)-camptothecins被引量:1
《Chinese Chemical Letters》2008年第10期1202-1205,共4页Di Zao Li Xian Dao Pan Hong Yan Liu Song Wu 
A series of 5-C-alkylating camptothecins have been synthesized by one-step method, and their in vitro antitumor activity was evaluated against six human cancer cell lines. The results showed that all 5-C-alkylates of ...
关键词:CAMPTOTHECIN SYNTHESIS 5-C-Alkylate Antitumor activity 
Synthesis and antitumor activity of heterocyclic acid ester derivatives of 20S-camptothecins
《Chinese Chemical Letters》2007年第11期1335-1338,共4页Di Zao Li Yan Li Xiao Guang Chen Chen Gen Zhu Jing Yang Hong Yan Liu Xian Dao Pan 
A series of heterocyclic acid esters of camptothecins as new compounds had been synthesized by acylation method, their in vitro and in vivo antitumor activities were evaluated. The cytotoxic results showed that 6 poss...
关键词:CAMPTOTHECIN SYNTHESIS Heterocyclic acid Antitumor activity 
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