SONOTHROMBOLYSIS

作品数：4被引量：11H指数：2
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Rotational Intravascular Multidirectional Ultrasound Catheter for Sonothrombolysis of Retracted Clots:An in Vitro and in Vivo Study
《Engineering》2024年第11期235-243,共9页Huaiyu Wu Jinwook Kim Bohua Zhang Gabe Owens Greyson Stocker Mengyue Chen Benjamin C.Kreager Ashley Cornett Kathlyne Bautista Tarana Kaovasia Paul A.Dayton Zhen Xu Xiaoning Jiang 
supported by National Institute of Health(NIH)grants(R01HL141967 and R21EB027304).
Thromboembolism in blood vessels poses a serious risk of stroke,heart attack,and even sudden death if not properly managed.Sonothrombolysis combined with ultrasound contrast agents has emerged as a promising approach ...
关键词：Intravascular ultrasound catheter Sonothrombolysis in vivo Retracted clots thrombolysis 
A Model of High-Speed Endovascular Sonothrombolysis with Vortex Ultrasound-Induced Shear Stress to Treat Cerebral Venous Sinus Thrombosis被引量：2
《Research》2023年第1期1-13,共13页Bohua Zhang Huaiyu Wu Howuk Kim Phoebe J.Welch Ashley Cornett Greyson Stocker Raul G.Nogueira Jinwook Kim Gabe Owens Paul A.Dayton Zhen Xu Chengzhi Shi Xiaoning Jiang 
support from the National Institutes of Health(grant numbers R01HL141967,R41HL154735,and R21EB027304);support from the National Science Foundation(grant number CMMI-2142555);。
This research aims to demonstrate a novel vortex ultrasound enabled endovascular thrombolysis method designed for treating cerebral venous sinus thrombosis(CVST).This is a topic of substantial importance since current...
关键词：THROMBOLYSIS DRUGS VORTEX 
Nanodroplet-mediated catheter-directed sonothrombolysis of retracted blood clots被引量：1
《Microsystems & Nanoengineering》2021年第1期77-83,共7页Leela Goel Huaiyu Wu Bohua Zhang Jinwook Kim Paul A.Dayton Zhen Xu Xiaoning Jiang 
supported by National Institutes of Health grant R01HL141967。
One major challenge in current microbubble(MB)and tissue plasminogen activator(tPA)-mediated sonothrombolysis techniques is effectively treating retracted blood clots,owing to the high density and low porosity of retr...
关键词：THROMBOLYSIS directed BOILING 
In vivo evaluation of urokinase-loaded hollow nanogels for sonothrombolysis on suture embolization-induced acute ischemic stroke rat model被引量：9
《Bioactive Materials》2018年第1期102-109,共8页Yuming Teng Haiqiang Jin Ding Nan Mengnan Li Chenghe Fan Yuanyuan Liu Pu Lv Wei Cui Yongan Sun Hongjun Hao Xiaozhong Qu Zhenzhong Yang Yining Huang 
This work is financially supported by the National Natural Science Foundation of China(81400941,51473169).
The urokinase-type plasminogen activator(uPA)loaded hollow nanogels(nUK)were synthesized by a one-step reaction of glycol chitosan and aldehyde capped poly(ethylene oxide).The resultant formulation is sensitive to dia...
关键词：Hollow nanogel Ultrasound responsive Urokinase delivery THROMBOLYSIS In vivo evaluation 
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