SPHINGOSINE

作品数：80被引量：236H指数：8
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相关领域：医药卫生更多>>
相关作者：张翼肖琼尹大力徐美林王菁更多>>
相关机构：北京协和医学院首都医科大学天津市胸科医院天津医科大学更多>>
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相关基金：国家自然科学基金广东省自然科学基金北京市自然科学基金国家重点基础研究发展计划更多>>
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Unveiling the biological role of sphingosine-1-phosphate receptor modulators in inflammatory bowel diseases被引量：4
《World Journal of Gastroenterology》2023年第1期110-125,共16页Evanthia Tourkochristou Athanasia Mouzaki Christos Triantos 
Inflammatory bowel disease(IBD)is chronic inflammation of the gastrointestinal tract that has a high epidemiological prevalence worldwide.The increasing disease burden worldwide,lack of response to current biologic th...
关键词：Inflammatory bowel disease Sphingosine-1-phosphate Intestinal inflammation T helper 1/T helper 17 Sphingosine 1 phosphate Modulators Immune responses 
FTY720,a sphingosine analog,altered placentome histoarchitecture in ewes
《Journal of Animal Science and Biotechnology》2020年第2期380-392,共13页Kathrin A.Dunlap Bryan G.White David W.Erikson M.Carey Satterfield Christiane Pfarrer Guoyao Wu Fuller W.Bazer Robert C.Burghardt Kayla J.Bayless Greg A.Johnson 
National Research Initiative Competitive Grant No.2009-35203-05725(KJB and GAJ);Fellowship No.2008-35203-18830(KAD)from the USDA National Institute of Food and Agriculture.
Background:The lysosphingolipid,sphingosine-1-phosphate,is a well-described and potent pro-angiogenic factor.Receptors,as well as the sphingosine phosphorylating enzyme sphingosine kinase 1,are expressed in the placen...
关键词：Placentome Pregnancy SHEEP Sphingosine1 phosphate(S1P) 
Vascular protection by high-density lipoprotein-associated sphingosine-1- phosphate被引量：4
《Journal of Geriatric Cardiology》2017年第11期696-702,共7页Xi WANG Fan WANG 
Epidemiological studies and animal experiments have consistently demonstrated cardiovascular protection by high-density lipoprotein （HDL）. Findings from a growing number of studies further indicate that sphingosine-...
关键词：APOM HDL-associated S1P Vascular function 
Incorporation of Sphingosine 1-Phosphate Loaded Mesoporous Silica Nanoparticles into Poly ( L-lactic acid ) Nanofibrous Scaffolds for Bone Tissue Engineering
《Journal of Donghua University(English Edition)》2017年第1期164-166,共3页秦明 周小军 张骞骞 苗莹珂 何创龙 
National Natural Science Foundations of China(Nos.31271028,31570984);International Cooperation Fund of the Science and Technology Commission of Shanghai Municipality,China(No.15540723400);Open Foundation of State Key Laboratory for Modification of Chemical Fibers,Polymer Materials,China(No.LK1416);the Innovation Funds of Donghua University,China(No.15D310516);“111 Project” Biomedical Textile Materials Science and Technology,China(No.B07024)
Controlled release of the functional factors is the key to improve clinical therapeutic efficacy during the tissue repair and regeneration. The thrce-dimensional （3D） scaffold can provide not only physical propertie...
关键词：SCAFFOLD mesoporous silica nanoparticles sphingosine 1- phosphate （ALP） RELEASE 
Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism被引量：17
《Acta Pharmaceutica Sinica B》2015年第2期151-157,共7页Eric Kwong Yunzhou Li Phillip B.Hylemon Huiping Zhou 
supported by A.D.Williams Award (to Huiping Zhou);National Institutes of Health (NIH,No.R01 DK-057543 to Phillip B.Hylemon and Huiping Zhou);supported by VA Merit Awards (No.1BX0013828-01 to Phillip B.Hylemon;No.1I01BX001390 to Huiping Zhou)
The liver is the central organ involved in lipid metabolism. Dyslipidemia and its related disorders, including non-alcoholic fatty liver disease(NAFLD), obesity and other metabolic diseases, are of increasing public h...
关键词：Bile acid Sphingosine-1 phosphate receptor Heptic lipid metabolism 
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