PROTHROMBINASE

作品数:5被引量:27H指数:3
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相关领域:医药卫生更多>>
相关期刊:《World Journal of Gastroenterology》《World Journal of Clinical Infectious Diseases》更多>>
相关基金:国家重点基础研究发展计划国家自然科学基金更多>>
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Physiological functions and clinical implications of fibrinogen-like 2:A review被引量:3
《World Journal of Clinical Infectious Diseases》2013年第3期37-46,共10页Genyan Yang W Craig Hooper 
Fibrinogen-like 2(FGL2) encompasses a transmembrane(m FGL2) and a soluble(s FGL2) form with differential tertiary structure and biological activities. Typically, m FGL2 functions as prothrombinase that is capable of i...
关键词:Fibrinogen-like 2 PROTHROMBINASE IMMUNOSUPPRESSOR INFECTIOUS disease 
Expression and Significance of fgl2 Prothrombinase in Cardiac Microvascular Endothelial Cells of Rats with Type 2 Diabetes被引量:6
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2010年第5期575-581,共7页丁艳萍 刘坤 汪艳 苏冠华 邓荷萍 曾秋棠 廖玉华 王朝晖 
supported by CGICC Medical Science Research Supporting Program (No.08010022);National Key Basic Research Program of China (No.2007CB512000,Sub-Project No.2007CB512005)
Microthrombosis may be involved in the pathogenesis of cardiac microangiopathy due to diabetes.Recent studies have shown that fibrinogen-like protein 2 (fgl2) plays a pivotal role in microthrombosis in viral hepatitis...
关键词:fibrinogen-like protein 2 type 2 diabetes ischemic heart disease MICROANGIOPATHY tumor necrosis factor-α cardiac function 
Construction of Plasmids Expressing Sars-CoV Encoding Proteins and Their Effects on Transcription of Hfgl2 Prothrombinase被引量:1
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2009年第3期318-323,共6页王洪武 韩梅芳 姚华宁 王战会 习东 严伟明 侯金林 罗小平 宁琴 
supported by a grant from National Key Project of Science and Technology Ministry of China for 973-SARS (No. 2003CB514112);SARS funding first granted from Ministry of education of China ([2003]64);The National 10th Five-Year Plan Key Project of China (2004BA720A01)
SARS coronavirus (SARS-CoV) is the etiologic agent of severe acute respiratory syndrome. The aim of this study was to construct Sars-CoV membrane (M), nucleocapsid (N) and spike 2 ($2) gene eukaryotic expressi...
关键词:SARS-COV encoding protein gene expression 
Fibrinogen-like protein 2/fibroleukin prothrombinase contributes to tumor hypercoagulability via IL-2 and IFN-γ被引量:20
《World Journal of Gastroenterology》2008年第39期5980-5989,共10页Kai Su Fang Chen Wei-Ming Yan Qi-Li Zeng Li Xu Dong Xi Bin Pi Xiao-Ping Luo Qin Ning 
The Natural Science Foundation of China,NSFC (30672380,30571643);National Key Basic Research Program of China (2007CB512900,2005CB522901,2005CB522507);11th Five-Year Plan Key Project (2006BAI05A07)
AIM: To examine the role of Fibrinogen-like protein 2 (fgl2)/fibroleukin in tumor development. Fgl2 has been reported to play a vital role in the pathogenesis in MHV-3 (mouse hepatitis virus) induced fulminant an...
关键词:Fibrinogen-like protein 2/fibroleukin Thrombin TUMOR Coagulation Cytokine 
Expression of Prothrombinase/fibroleukin Gene fg12 in Lung Impairment in a Murine Severe Acute Respiratory Syndrome Model被引量:1
《中国病毒学》2007年第3期181-192,共12页Wei-ming YAN  Jia-quan HUANG  Xiao-ping LUO Qin NING 
National 973 project of Chnia for SARS study (2003CB514112); Ministry of Education of China for SARS study (2003-18); National Science Fund for Distinguished Young Investigators (30225040,. 30123019).
To evaluate the role of murine fibrinogen like protein 2 (mfgl2) /fibroleukin in lung impairment in Severe acute respiratory syndrome (SARS), a murine SARS model induced by Murine hepatitis virus strain 3 (MHV-3) thro...
关键词:凝血酶原酶 fg12基因 肺损伤 急性呼吸综合征 基因表达 
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