Fibrinogen-like 2(FGL2) encompasses a transmembrane(m FGL2) and a soluble(s FGL2) form with differential tertiary structure and biological activities. Typically, m FGL2 functions as prothrombinase that is capable of i...
supported by CGICC Medical Science Research Supporting Program (No.08010022);National Key Basic Research Program of China (No.2007CB512000,Sub-Project No.2007CB512005)
Microthrombosis may be involved in the pathogenesis of cardiac microangiopathy due to diabetes.Recent studies have shown that fibrinogen-like protein 2 (fgl2) plays a pivotal role in microthrombosis in viral hepatitis...
supported by a grant from National Key Project of Science and Technology Ministry of China for 973-SARS (No. 2003CB514112);SARS funding first granted from Ministry of education of China ([2003]64);The National 10th Five-Year Plan Key Project of China (2004BA720A01)
SARS coronavirus (SARS-CoV) is the etiologic agent of severe acute respiratory syndrome. The aim of this study was to construct Sars-CoV membrane (M), nucleocapsid (N) and spike 2 ($2) gene eukaryotic expressi...
The Natural Science Foundation of China,NSFC (30672380,30571643);National Key Basic Research Program of China (2007CB512900,2005CB522901,2005CB522507);11th Five-Year Plan Key Project (2006BAI05A07)
AIM: To examine the role of Fibrinogen-like protein 2 (fgl2)/fibroleukin in tumor development. Fgl2 has been reported to play a vital role in the pathogenesis in MHV-3 (mouse hepatitis virus) induced fulminant an...
National 973 project of Chnia for SARS study (2003CB514112); Ministry of Education of China for SARS study (2003-18); National Science Fund for Distinguished Young Investigators (30225040,. 30123019).
To evaluate the role of murine fibrinogen like protein 2 (mfgl2) /fibroleukin in lung impairment in Severe acute respiratory syndrome (SARS), a murine SARS model induced by Murine hepatitis virus strain 3 (MHV-3) thro...