人类胚胎干细胞

作品数：390被引量：284H指数：7
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hESC-derived pancreatic progenitors
《Cell Research》2013年第5期592-594,共3页Lina Sui Guang-Hui Liu Juan Carlos Izpisua Belmonte 
Successful derivation of pancreatic progenitors from human embryonic stem ceils （hESCs） in vitro and further differentiation towards functional p cells in vivo may create the possibility of using hESC-derived pancre...
关键词：人类胚胎干细胞 祖细胞 胰腺 衍生 细胞分化 细胞来源 替代治疗 P细胞 
Sanofi-Cell Research outstanding paper award of 2011
《Cell Research》2012年第11期1511-1511,共1页DangshengLi 
We are pleased to announce the winners of the 3rd Sanofi-Cell Research Outstanding Paper Award, which were selected from papers published in the 2011 print issues of Cell Research. The 2011 Sanofi-Cell Research Outsta...
关键词：人类胚胎干细胞 优秀论文 菲 基因表达 组蛋白修饰 合作伙伴 研究论文 调控序列 
MLL-AF4 driven leukemogenesis： what are we missing？
《Cell Research》2012年第6期948-949,共2页Ronald W Stam 
Pre-leukemic MLL-AF4 fusions arise prenatally and typically read to overt acute lymphoblastic leukemia （ALL） at or shortly after birth. In a recent study, Bueuo and colleagues explored the effects of MLL-AF4 express...
关键词：淋巴细胞白血病 人类胚胎干细胞 驱动 
Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle被引量：54
《Cell Research》2011年第11期1638-1640,共3页ShengliYu  JunjieLuo  ZhiyuanSong  FangrongDing  YunpingDai NingLi 
Dear Editor, Gene targeting is in widespread use as a gold stan- dard for determining the function of genes in mice and human embryonic stem cells [1]. However, the poor ef- ficiency of this technology has hindered i...
关键词：基因打靶 Β-乳球蛋白 BLG 核酸酶 人类胚胎干细胞 修改 锌指 牛 
Mark the transition： chromatin modifications and cell fate decision被引量：2
《Cell Research》2011年第10期1388-1390,共3页Qiang Wu Huck-Hui Ng 
With their unique features of sell＇- renewal and pluripotency, human embryonic stem （hES） cells are considered to be a nearly unlimited resource for research and clinical applications [1]. Accordingly,
关键词：人类胚胎干细胞 染色质 修饰 临床应用 全能性 
Double knockouts in human embryonic stem cells
《Cell Research》2010年第3期250-252,共3页Jizhong Zou Rory Cochran Linzhao Cheng 
Gene targeting is the method of precise genome modification that utilizes the innate DNA repair mechanism in cells, known as homologous recombination. At its genesis, gene targeting in mouse embryonic stem （ES） cell...
关键词：人类胚胎干细胞 小鼠胚胎干细胞 诺贝尔生理学或医学奖 基因打靶 发育生物学 基因改造 细胞修复 同源重组 
Pancreatic differentiation from pluripotent stem cells： Tweaking the system
《Cell Research》2009年第4期395-396,共2页Andrew M Holland Andrew G Elefanty Edouard G Stanley 
Autoimmune destruction of insulin producing pancreatic β cells results in type 1 diabetes, a condition for which there is presently no cure. Clinical trials indicate that, in some instances, control of blood glucose ...
关键词：人类胚胎干细胞 胰腺癌 调整系统 多能性 细胞治疗 分化 胰岛移植 自身免疫性 
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