an ERC Advanced Investigator Grant(No.268476 BIOSILICA);an ERC Proof-of-Concept Grant(No.ERC-2012-PoC-324564);supported by grants from the Deutsche Forschungsgemeinschaft(Schr 277/10-2);the European Commission("BIOMINTEC":No.215507;and Industry-Academia Partnerships and Pathways"Core-Shell":No.286059;"SPECIAL":No.266033;"MarBioTec*EU-CN*":No.268476;and"BlueGenics":No.311848);the International Human Frontier Science Program,the Public Welfare Project of Ministry of Land and Resources of the People's Republic of China(Grant No.201011005-06);the International Science&Technology Cooperation Program of China(Grant No.2008DFA00980)