Objective To explore the anti-tumor effects induced by fusion of interleukin (IL) -18 gene transfected lung cancer cell line NCI-H460 cells with dendritic cells (DC). Methods (1) DC were induced from human monoc...
Objective To study the effect of dendritic cells (DCs) transfected with sCD40-EGFP on T-cell proliferation and the cytotoxic T lymphocyte cytotoxic activity. Methods The expressing vector pEGFP-N1 /sCD40 was transfe...
A 45-year-old male cook was seen for the evaluation and removal of a "mole o n my eye" of steady growth during the previous 6 months. The patient stated that he had had a "brown spot" above his left eye for 17 years p...
A novel inhibitory receptor of immunoglobin superfamily (IgSF), IgSF member 13 (IgSF13), has been identified from human dendritic cells (DC). IgSF13 is a type Ⅰ transmembrane protein containing an N-terminal signal p...
An effective immune response against human immunodeficiency virus or simian immunodeficiency virus (SIV) is critical in achieving control of viral replication. Here, we show in SIV-infected rhesus monkeys that an effe...
AIM: To investigate the effects of dendritic cells (DCs) transfected with full-length wild-type p53 and stimulated by gastric cancer lysates on immune response.METHODS: The wild-type p53 was transduced to DCs with ade...
Supported by the Postdoctoral Science Foundation of China,No.2003033531
AIM: To induce the tolerance of rat liver allograft by dendritic cells (DCs) modified with NF-κB decoy oligodeoxynucleotides (ODNs).METHODS: Bone marrow (BM)-derived DCs from SD rats were propagated in the presence o...