the support from the Alexander von Humboldt Foundation;supported by the National Basic Research Program of China(Grant No.2007CB310402);the 863 program of China;the National Natural Science Foundation of China(Grant No.60721004);the major projects(Project Nos.KGCX1-YW-24 and KGCX2-YW-231);the Hundred Talent Program of the Chinese Academy of Sciences;the Shanghai Municipal Commission of Science and Technology(Project No.10JC1417000)