Β-GALACTOSIDASE

作品数:33被引量:66H指数:4
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相关领域:生物学医药卫生更多>>
相关作者:罗利朱家壁俞冠翘刘芳华姚宇玫更多>>
相关机构:中国科学院上海生命科学研究院浙江大学医学院附属第一医院罗格斯,新泽西州立大学昆明理工大学更多>>
相关期刊:《Journal of Innovative Optical Health Sciences》《Cancer Biology & Medicine》《Acta Biochimica et Biophysica Sinica》《Food Bioscience》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金浙江省科技厅基金更多>>
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A β-galactosidase kiss of death for senescent cells被引量:1
《Cell Research》2020年第7期556-557,共2页Xiaoqian Liu Juan Carlos Izpisua Belmonte Weiqi Zhang Guang-Hui Liu 
In a recent paper published in Cell Research,Cai et al.report development of the prodrug senescence-specific killing compound 1(SSK1),which specifically clears SA-β-galactosidase-positive senescent cells both in vitr...
关键词:INFLAMMATION HOMEOSTASIS predominant 
Elimination of senescent cells byβ-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice被引量:21
《Cell Research》2020年第7期574-589,共16页Yusheng Cai Huanhuan Zhou Yinhua Zhu Qi Sun Yin Ji Anqi Xue Yuting Wang Wenhan Chen Xiaojie Yu Longteng Wang Han Chen Cheng Li Tuoping Luo Hongkui Deng 
This work was supported by National Key Research and Development Program of China(2017YFA0104003,2017YFA0103000);the National Natural Science Foundation of China(22040102 and 31521004 to H.D.and T.L.,31730059 to H.D.,21672011 and 21822101 to T.L.).
Cellular senescence,a persistent state of cell cycle arrest,accumulates in aged organisms,contributes to tissue dysfunction,and drives age-related phenotypes.The clearance of senescent cells is expected to decrease ch...
关键词:INFLAMMATION eliminate function 
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