supported by the National Key Research and Development Program of China(Nos.2022YFC2502600 and 2022YFC2502606);the National Natural Science Foundation of China(Nos.82170206 and 82170208);CAMS Innovation Fund for Medical Sciences(Nos.2019-I2M-5-034 and 2022-I2M-C&T-B-121);Peking University People’s Hospital Research and Development Funds(No.RZ2022-02);Tongzhou District Distinguished Young Scholars(No.JCQN2023009);Shanghai Municipal Health Commission Project of Disciplines of Excellence(No.20234Z0002)。
The cooccurrence of NPM1,FLT3-ITD,and DNMT3A mutations(i.e.,triple mutation)is related to dismal prognosis in patients with acute myeloid leukemia(AML)receiving chemotherapy alone.In this multicenter retrospective coh...
Objective To investigate the effect of clonal hematopoiesis (CH) in remission on hematopoiesis recovery in patients with NPM1 mutated acute myeloid leukemia (AML) after chemotherapy.Methods Retrospective analysis was ...
supported by the National Key Research and Development Program of China(Grant No.2021YFA1201100);the National Natural Science Foundation of China(Grant Nos.82103006,82030092,81720108028,82072657,82072716,82103003,82173295,81871968,81871978,82072691,and 82103222);the Tianjin Hygiene Healthy Science and Technology Project(Grant No.TJWJ2022MS007);the Science&Technology Development Fund of Tianjin Education Commission for Higher Education(Grant No.2020KJ141).
Objective:Pancreatic ductal adenocarcinoma(PDAC)is a highly malignant gastrointestinal cancer with a 5-year survival rate of only 9%.Of PDAC patients,15%-20%are eligible for radical surgery.Gemcitabine is an important...