supported by the National Natural Science Foundation of China (82002155 to T.S., and U21A20423 and 31670161 to X.Z.)
RNA-remodeling proteins,including RNA helicases and chaperones,play vital roles in the remodeling of structured RNAs.During viral replication,viruses require RNA-remodeling proteins to facilitate proper folding and/or...
supported by the Strategic Priority Research Program of CAS(XDB29010300 to X.Z.);National Natural Science Foundation of China(81873964 to Y.Q.,31800140 to J.M.and 31670161 to X.Z.);National Science and Technology Major Project(2018ZX10101004 to X.Z.);the Science and Technology Development Fund,Macao SAR(0007/2020/A to R.W)。
The ongoing outbreak of Coronavirus Disease 2019(COVID-19)has become a global public health emergency.SARScoronavirus-2(SARS-CoV-2),the causative pathogen of COVID-19,is a positive-sense single-stranded RNA virus belo...
supported by the grants from the National Special Research Fund for Public Welfare (Agriculture) of China (200803017 and 200903036-06)
Nucleoside triphosphate hydrolase (NTPase) is a multifunctional enzymatic family widely existing in vivo. They can hydrolyze NTP to NMP or dNTP to dNMP to produce energy. In this article, the structure of Toxoplasma...