OLIGONUCLEOTIDES

作品数:75被引量:205H指数:6
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相关领域:医药卫生生物学更多>>
相关作者:王晶刘张岚高运华张玲张礼和更多>>
相关机构:北京大学中国计量科学研究院湖南医科大学北京大学第一医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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Tuning the Stability of the Polyplex Nanovesicles of Oligonucleotides via a Zinc(Ⅱ)-Coordinative Strategy
《Chinese Journal of Polymer Science》2022年第9期1034-1042,共9页Quan Zhou Xiang Li Jia-Jia Xiang You-Qing Shen 
financially supported by the National Key Research and Development Program of China (No.2021YFA1201200);the National Natural Science Foundation of China (Nos. 51833008, 52173141 and 82102192);Zhejiang Provincial Key Research and Development Program (No.2020C01123);China Postdoctoral Science Foundation (No.2019M662059)
Oligonucleotide therapeutics have great potential to target the currently undruggable genes and to generate entirely new therapeutic paradigms in multiple types of disease,thus having attracted much attention in recen...
关键词:Oligonucleotide therapeutics Polyplex nanovesicles Coordinative cationic block Lysosome-targeting 
Poly(1-vinylimidazole) Prospects in Gene Delivery被引量:1
《Chinese Journal of Polymer Science》2019年第7期637-645,共9页Elena N.Danilovtseva Stanislav N.Zelinskiy Viktor A.Pal'shin Gayathri Kandasamy Uma Maheswari Krishnan Vadim V.Annenkov 
financial support from a joint grant of the Russian Science Foundation (16-45-02001);the Department of Science Technology of the Ministry of Science and Technology of the Republic of India (INT/RUS/RSF/10)
Polymeric amines are being studied intensively as components of systems for gene delivery in genetic engineering and gene therapy of genetic disorders, including cancer. Despite remarkable achievements in the field, p...
关键词:POLYMERIC AMINES OLIGONUCLEOTIDES Fluorescence Poly(1-vinylimidazole) Gene delivery 
Bioinspired Water-soluble Polymers with Grafted Polyamine Chains: Synthesis and Complexation with Oligonucleotides
《Chinese Journal of Polymer Science》2018年第10期1114-1122,共9页Vadim V.Annenkov Uma Maheswari Krishnan Viktor A.Pal'shin Stanislav N.Zelinskiy Gayathri Kandasamy Elena N.Danilovtseva 
financial support from a joint grant of the Russian Science Foundation(#6-45-02001);the Department of Science Technology of the Ministry of Science and Technology of the Republic of India(#INT/RUS/RSF/10)
The siliceous frustules of diatom algae contain complex proteins known as silaffins, which consist of a peptide chain with grafted polyamine chains. These polyamines contain twenty or more nitrogen atoms with trimethy...
关键词:POLYAMINE Polymeric amine Gene delivery Acryloyl chloride 
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