the National Natural Science Foundation of China(No.51373067).
A straiglitforward and efficient synthetic method of 2′-(dialkylammo)-l-alkyl-4′H-spiro[indoline-3,5′-oxazole]-2,4′-diones and 2-(dialkylamino)-5,6-dihydro-4H-naphtho[2,1-e][1,3]oxazin-4-one-derivatives have been ...
the Key Projects in the National Science & Technology Pillar Program of China,the Program for New Century Excellent Talents in University,China,the National Natural Science Foundation of China,the Natural Science Foundation of Tianjin City,China
A simple and efficient method has been developed for highly diastcreoselective synthesis of trans-1,1-disubstituted-2,6-diarylcyclohexane-4-ones from dibenzalacetone and malononitril with trans-1,2-diaminocyclohexane ...
Multi-component condensation of 2-naphthol, aromatic aldehydes, and cyclic 1,3-dicarbonyl compounds catalyzed by ionic liquid [NSPTEA][HSO4] was accomplished for the synthesis of a series of 12-aryl-8,9,10,12- tetrahy...
Supported by the National Natural Science Foundation of China(No.21175031);the Program for Science and Technology Development of Hebei Province, China(No.11966411D);the Fund of Key Laboratory for Pharmaceutical Quality Control of Hebei Province, China(No.09265631D-14);the Fund of Hebei University, China(No. 2010Q33);the Fund of Hebei Provincial Department of Education, China(Nos.ZD2010234, 2011159)
A series of 3-substituedmethylenethiochroman-4-ones was designed and synthesized, and their structures were confirmed by 1H NMR, 13C NMR, MS, IR, UV and elemental analysis. The results of their anticancer activity stu...
Supported by the Mid-young Scholar's Science and Technology Program of the Education Department of Hubei Province,China(No.Q20082202)
An efficient method is described for the synthesis of 2-substituted quinolino[7',8':5~6]pyrano[2,3-d] pyrimidin-4(3H)-ones(6) via a tandem aza-Wittig annulation process. The iminophosphorane(3) reacted with a...
Supported by the Natural Science Foundation of Liaoning Province(No. 20032043)
A series of novel pyrazolo [ 4,3-d ] pyrimidin-7-ones was designed and synthesized in order to find new potent phosphodiesterase 5 inhibitors(PDE5). The structures of all the compounds were confirmed by IR, ^1H NMR ...
The mass spectrometric fragmentation of 2a,4-disubstituted 5-benzoyl-2a,3,4,5-tetrahydro-2-phenoxy-azeto{[1,2-a]}[1,5]benzodiazepin-1(2H)-ones has been investigated by means of mass-analyzed ion kinetic energy spectro...
The 2(5H)-furanone and 3(6H)-pyranone structures are frequently found in natural products, which have a broad range of biological activities. In addition, furanones and pyranones have served as versatile intermediates...