supported by the Natural Science Foundation of Guangdong Province(2022A1515010297);the National Natural Science Foundation of China(32100765);the Xiamen Medical Health Science and Technology Project(3502Z20194098);the Shenzhen-Hong Kong-Macao Science and Technology Innovation Project(SGDX2020110309280100).
Dear Editor,Sturge-Weber Syndrome(SWS)is a rare congenital neurocutaneous syndrome[1,2],with an estimated prevalence of 0.19 in 100,000 annually[3].It is a non-hereditary disease linked to a somatic mutation in the GN...
Supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education,No.NRF-RS-2023-00237287 and No.NRF-2021S1A5A8062526;Local Government-University Cooperation-Based Regional Innovation Projects,No.2021RIS-003.
Heterotopic mesenteric ossification(HMO)is a rare medical condition,with<100 cases reported globally by 2024.This disorder is characterized by abnormal bone tissue formation within the mesentery,often following abdomi...
Supported by Major Basic Research Project of Shanxi Provincial Natural Science Foundation,No.202203021221185 and No.202103021224379.
BACKGROUND Among all forms of heterotopic ossification,heterotopic mesenteric ossification(HMO)is rare,with fewer than 100 reported cases to date.Postoperative early small bowel obstruction caused by HMO is even rarer...
National Natural Science Foundation of China(Grant Nos.82261160397,82272560);Central South University Research Programme of Advanced Interdisciplinary Studies(2023QYJC011);National Natural Science Foundation of China(Grant Nos.82472521,81922017);Hunan Provincial Science and Technology Department(2023JJ30896);Key Research and Development Program of Hunan Province(2022SK2023);Science and Technology Innovation Program of Hunan Province(2023RC1027);Major Basic Research Projects in Hunan Province(No.2024JC0004)。
Mechanical stress modulates bone formation and organization of the extracellular matrix(ECM),the interaction of which affects heterotopic ossification(HO).However,the mechanically sensitive cell populations in HO and ...
supported by grants from the Ministry of Science and Technology of the People’s Republic of China(No.2022YFA1104003 to Hongquan Zhang and No.2021YFC2501003 to Hongquan Zhang);the National Natural Science Foundation of China(No.82073076 to Yu Yu,No.82372992 to Yu Yu,No.82230094 to Hongquan Zhang and No.81972616 to Hongquan Zhang,and No.82372451 to Xiaoguang Liu).
Ossification of the posterior longitudinal ligament(OPLL)is a condition comprising ectopic bone formation from spinal ligaments.This disease is a leading cause of myelopathy in the Asian population.However,the molecul...
Supported by Natural Science Foundation of Fujian Province,China No.2021J01545;Natural Science Foundation of Zhangzhou City,Fujian Province,China No.ZZ2021J25.
BACKGROUND Heterotopic mesenteric ossification(HMO)is a clinically rare condition characterized by the formation of bone tissue in the mesentery.The worldwide reporting of such cases is limited to just over 70 instanc...
This work was supported by the National Nature Science Foundation of China grant 82170978(to K.J.);the Distinguished Young Scientists Funds of Shannxi Province 2021JC-34(to K.J.).
Brain-derived extracellular vesicles participate in interorgan communication after traumatic brain injury by transporting pathogens to initiate secondary injury.Inflammasome-related proteins encapsulated in brain-deri...
supported by the German Research Foundation(SCHI 504/19-1(to TS)and IG 18/22-1(to AI));the Else Kröner-Fresenius foundation under grant no.2021_EKEA.23(to TR);financial support from the Open Access Publication Fund of UKE–Universitatsklinikum Hamburg-Eppendorf and DFG–German Research Foundation.
Piezo proteins are mechanically activated ion channels,which are required for mechanosensing functions in a variety of cell types.While we and others have previously demonstrated that the expression of Piezo1 in osteo...
supported by the National Natural Science Foundationof China (No. 33372201)。
The endochondral ossification of hindlimb is essential to a bird’s ability to stand,walk and fly.Most hindlimb is ossified in the embryos before hatching in precocial birds.However,the molecular mechanisms of hindlim...
BACKGROUND Phlebosclerosis is a common age-related fibrotic degeneration of the venous wall.It is a disorder rather than a disease,which may cause venous dysfunction and even venous thrombosis.It is rarely reported in...