financially supported by the National Natural Science Foundation of China(Nos.22075209,U20A20260 and 52103180);a distinguished professor of Tianjin,the Leading Talents Program of the Tianjin Educational Committee;the Key program of Tianjin Municipal Natural Science Foundation(Nos.18JCZDJC37700 and 18JCQNJC72300);the Training Project of Innovation Team of Colleges and Universities in Tianjin(No.TD13-5020);the Tianjin Enterprise Key Laboratory for Application Research of Hyaluronic Acid(No.KTRDHA-Z201901)for the financial support。
Oxaliplatin is the common chemotherapy drug for the treatment of colorectal cancer(CRC),however,the harmful Fusobacterium nucleatum(Fn)that existed in the CRC tumor tissues leads to extreme drug resistance to oxalipla...
supported by the National Natural Science Foundation of China(Grant Nos.21874078,22074072,and 22274083);the Taishan Young Scholar Program of Shandong Province(Grant No.tsqn20161027);the China Postdoctoral Science Foundation(Grant No.2018M630752);the Postdoctoral Scientific Research Foundation of Qingdao;the Innovation and Development Joint Fund of Natural Science Foundation of Shandong Province(Grant No.ZR2022LZY022);the Science and Technology Planing Project of South District of Qingdao City(Grant No.2022-4-005-YY);the Exploration Project of the State Key Laboratory of Bio Fibers and EcoTextiles of Qingdao University(Grant No.TSKT202101);the High Level Discipline Project of Shandong Province。
Poly(amidoamine)(PAMAM)dendrimers are widely studied as drug vectors due to their particular structure and excellent properties.Drug molecules can be loaded in the internal cavity of dendrimers or adsorbed on the surf...