PARKINSONS_DISEASE

作品数：727被引量：1588H指数：17
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Chinese guidelines on remote programming of deep brain stimulation for patients with Parkinson’s disease
《Chinese Medical Journal》2025年第3期261-263,共3页Fangang Meng Jie Zhang Wenbin Zhang Ling Chen Jianjun Wu Shanshan Mei Lijuan Wang Jianguo Zhang The Chinese Medical Association Neurosurgery Branch of Functional Neurosurgery Group The Chinese Medical Association Neurology Branch of Parkinson’s Disease,Movement Disorders Group The Chinese Physician Association Neurosurgeon Branch of Functional Neurosurgery Expert Committee The Chinese Physician Association Neurologist Branch of Parkinson’s Disease and Movement Disorders Professional Committee China Neuromodulation Union Society Whole-process Management of Neuromodulation and Chinese Expert Committee on Deep Brain Stimulation for Parkinson’s Disease 
National Key Research and Development Program of China(Nos.2022YFC2405100 and 2021YFC2401200);National Natural Science Foundation of China(No.81830033);Key R&D Program of Jiangsu Science and Technology Project(No.BE2022049);Key Research and Development Program of Henan Province(No.241111310100)
Deep brain stimulation(DBS)is a neurosurgical procedure that allows targeted circuit-based neuromodulation;it is also a standard of care for Parkinson’s disease(PD).[1]Postoperative DBS programming is a crucial step ...
关键词：stimulation parameters neurosurgical procedure deep brain stimulation dbs release symptoms parkinson s disease which remote programming postoperative programming deep brain stimulation 
Gut microbiota and Parkinson’s disease
《Chinese Medical Journal》2025年第3期289-297,共9页Lin Wang Ying Cui Bingyu Han Yitong Du Kenish Sirajbhai Salewala Shiya Wang Wenlu Zhao Hongxin Zhang Sichen Wang Xinran Xu Jianpeng Ma Yan Zhu Houzhen Tuo 
National Natural Science Foundation of China(Nos.82071257 and 82371254);Beijing Municipal Bureau of Economy and Information Technology(No.JX2023YJ021)
Emerging evidence suggests that dysbiosis of the gut microbiota is associated with the pathogenesis of Parkinson’s disease(PD),a prevalent neurodegenerative disorder.The microbiota-gut-brain axis plays a crucial role...
关键词：Parkinson’s disease Microbiota-gut-brain axis Gut microbiota NEUROINFLAMMATION METABOLISM 
Slow wave activity in patients with Parkinson’s disease and obstructive sleep apnea
《Chinese Medical Journal》2024年第19期2378-2380,共3页Mengxing Tao Yun Shen Lin Meng Hanxing Li Fen Wang Chengjie Mao Xinling Yang Chunfeng Liu 
supported by grants from the National Key R&D Program of China(No.2017YFC 0909100);Jiangsu Provincial Medical Key Discipline(No.ZDXK202217);Suzhou Technology Development Programme(No.SLT201924 and SKJY2021090);Discipline Construction Program of the Second Affiliated Hospital of Soochow University(No.XKTJ XK202001);Science and Technology Innovation Project of Xiongan New Area(No.2023XAGG0073);Jiangsu Provincial Medical Key Discipline(No.ZDXK202217);Suzhou Key Laboratory(No.SZS2023015);the National Key R&D Program of China(No.2022YFC2503904).
To the Editor:Obstructive sleep apnea(OSA)is one of the common sleep disorders in Parkinson’s disease(PD)that is often associated with sleep fragmentation and intermittent hypoxemia.[1]Clinically,it has been observed...
关键词：SLEEP alterations APNEA 
Non-genetic risk factors of Parkinson’s disease:A large meta-analysis and systematic review
《Chinese Medical Journal》2024年第15期1873-1875,共3页Kangfu Yin Weiming Su Xiaojing Gu Zheng Jiang Qingqing Duan Bei Cao Liyi Chi Yongping Chen 
supported by grants from the National Natural Science Fund of Sichuan(No.2022NSFSC0749);the 1·3·5 project for disciplines of excellence-Clinical Research Fund,West China Hospital,Sichuan University(No.2023HXFH032);the Science and Technology Bureau Fund of Sichuan Province(No.2023YFS0269).
To the Editor:In the recent decades,significant global endeavors have been undertaken to investigate the risk factors associated with Parkinson’s disease(PD)and to enhance the evidence on PD prevention.[1]However,the...
关键词：ANALYSIS FOUNDING prevailing 
Comparing the effects of dual-task training and single-task training on walking,balance and cognitive functions in individuals with Parkinson’s disease:A systematic review
《Chinese Medical Journal》2024年第13期1535-1543,共9页Xiaoying Lin Yanming Zhang Xiaowei Zhang Xi Chen Jianhua Liu Lei Yang Marco Yiu Chung Pang 
Kunming Health Science and Technology Talent Training Project,Training Plan for Medical Science and Technology Discipline Leaders(No.2022-SW[Leaders]-27)
Background:This systematic review aimed to examine whether dual-task(DT)training was superior to single-task(ST)training in improving DT walking,balance and cognitive functions for individuals with Parkinson’s diseas...
关键词：Parkinson’s disease Dual-task training Mobility COGNITION Systematic review 
Motor symptom machine rating system for complete MDS-UPDRS III in Parkinson’s disease:A proof-of-concept pilot study
《Chinese Medical Journal》2024年第13期1632-1634,共3页Xue Zhu Zhonglue Chen Yun Ling Ningdi Luo Qianyi Yin Yichi Zhang Aonan Zhao Guanyu Ye Haiyan Zhou Jing Pan Liche Zhou Linghao Cao Pei Huang Pingchen Zhang Cheng Chen Weikun Shi Shinuan Lin Haimei Zhuang Jin Zhao Kang Ren Yuyan Tan Jun Liu 
To the Editor:Parkinson’s disease(PD)is one of the most common neurodegenerative movement disorders.[1]The severity of PD-related motor symptoms is usually semiquantitatively(“normal”,“slight”,“mild”,“moderate...
关键词：MDS PROOF SEVERITY 
Genetic analysis of transcription factors in dopaminergic neuronal development in Parkinson’s disease
《Chinese Medical Journal》2024年第4期450-456,共7页Yuwen Zhao Lixia Qin Hongxu Pan Tingwei Song Yige Wang Xiaoxia Zhou Yaqin Xiang Jinchen Li Zhenhua Liu Qiying Sun Jifeng Guo Xinxiang Yan Beisha Tang Qian Xu 
supported by grants from the National Natural Science Foundation of China(Nos.82071437,U20A20355,and 82101342);the Hunan Innovative Province Construction Project(No.2019SK2335);the Natural Science Foundations of Hunan Province(No.2021JJ31115);the National Key Research and Development Program of China(Nos.2016YFC1306000 and 2021YFC2502100);the Project Program of National Clinical Research Center for Geriatric Disorders(Xiangya Hospital)(No.2021KFJJ10)
Background:Genetic variants of dopaminergic transcription factor-encoding genes are suggested to be Parkinson’s disease(PD)risk factors;however,no comprehensive analyses of these genes in patients with PD have been u...
关键词：Parkinson’s disease Transcription factors Dopaminergic neurons GENETIC VARIANTS 
Contactless evaluation of rigidity in Parkinson’s disease by machine vision and machine learning被引量：1
《Chinese Medical Journal》2023年第18期2254-2256,共3页Xue Zhu Weikun Shi Yun Ling Ningdi Luo Qianyi Yin Yichi Zhang Aonan Zhao Guanyu Ye Haiyan Zhou Jing Pan Liche Zhou Linghao Cao Pei Huang Pingchen Zhang Zhonglue Chen Cheng Chen Shinuan Lin Jin Zhao Kang Ren Yuyan Tan Jun Liu 
National Natural Science Foundation of China(Nos.82230040,82071415,and 81971183);Shanghai Jiao Tong University Trans-med Awards Research(No.20220103)
To the Editor:Parkinson’s disease(PD)is one of the most common neurodegenerative movement disorders.[1]Its cardinal symptoms include bradykinesia,tremor,and rigidity.[2]The severity of PD-related motor symptoms is us...
关键词：RIGIDITY SEVERITY TREMOR 
Gut microbiota:a new insight into neurological diseases被引量：2
《Chinese Medical Journal》2023年第11期1261-1277,共17页Lanxiang Liu Haiyang Wang Xueyi Chen Peng Xie 
National Key R&D Program of China(No.2017YFA0505700);Non-Profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(No.2019PT320002);Natural Science Foundation Project of China(No.81820108015);China Postdoctoral Science Foundation(Nos.2020TQ0393,2020M683634XB,and 2021M693926);Chongqing Science and Technology Commission(Nos.cstc2021jcyj-bsh0026 and cstc2021jcyj-bsh0034)
In the last decade,it has become increasingly recognized that a balanced gut microbiota plays an important role in maintaining the health of the host.Numerous clinical and preclinical studies have shown that changes i...
关键词：Gut microbiota Gut-brain axis Neurological diseases Parkinson’s disease Alzheimer’s disease Autism spectrum disorder Cerebrovascular disease 
Current applications for magnetic resonance-guided focused ultrasound in the treatment of Parkinson’s disease被引量：2
《Chinese Medical Journal》2023年第7期780-787,共8页Haoxuan Lu Xiaoyu Wang Xin Lou 
National Natural Science Foundation of China(Nos.82151309,81825012)
Magnetic resonance-guided focused ultrasound(MRgFUS)is a novel and minimally invasive technology.Since the US Food and Drug Administration approved unilateral ventral intermediate nucleus-MRgFUS for medication-refract...
关键词：Magnetic resonance-guided focused ultrasound THERMOABLATION Blood-brain barrier Parkinson’s disease NEUROMODULATION 
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