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USP33, a new player in lung cancer, mediates Slit-Robo signaling被引量：2
《Protein & Cell》2014年第9期704-713,共10页Pushuai Wen Ruirui Kong Jianghong Liu Li Zhu Xiaoping Chen Xiaofei Li Yongzhan Nie Kaichun WU Jane Y. Wu 
ACKNOWLEDGEMENTS We gratefully thank Dr. Zhipei Zhang for the assistance in lung cancers sample collection. We thank Mang Zheng for technical assistance. We thank other members of Wu lab for stimulating dis- cussion and helpful suggestions. This work was supported by the National Basic Research Program （973 Program） （2010CB529603 and 2013CB917803） and the National Natural Science Foundation of China （Grant No. 91132710）. RK was supported by China Post- doctoral Science Foundation （20110490615）. JYW is supported by NIH （Nos. RO1AG033004 and RO1CA175360）. JYW designed the study; PW, XC and RK performed the experiments and analyzed the data; XL, YN and KW provided tissue samples and important suggestions; LZ, JL and JYW supervised the experiments and analyzed the data; PW and JYW wrote the paper.
Ubiquitin specific protease 33 （USP33） is a multifunctional protein regulating diverse cellular processes. The expression and role of USP33 in lung cancer remain unexplored. In this study, we show that USP33 is down...
关键词：USP33 SLIT ROBO lung cancer Slit-Robosignaling tumor suppressor prognostic marker 
TPP1 as a versatile player at the ends of chromosomes被引量：1
《Frontiers in Biology》2014年第3期225-233,共9页Sijie ZHANG 
Acknowledgements This study was supported by the National Basic Research Program （973 Program） （Nos. 2012CB911201 and 2010CB945401）, the National Natural Science Foundation （Grant Nos. 31371508, 91019020 and 81330055）, the Introduced Innovative R and D Team of Guangdong Province （No. 201001Y0104687244）, Zhujiang Program of Science and Technology Nova in Guangzhou （No. 2011 J2200082）.
Telomeres, the ends of linear eukaryotic chromosomes, are tandem DNA repeats and capped by various telomeric proteins. These nucleoprotein complexes protect telomeres from DNA damage response （DDR）, recombination, a...
关键词：TELOMERE TPP1 TIN2 telosome/shelterin TELOMERASE 
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