云南高校图书馆联盟文献共享服务平台- TELOMERASE

TELOMERASE: 作品数：280被引量：852H指数：13; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：丁健郑晖冯德云欧阳小明程瑞雪更多>>; 相关机构：中国科学院中南大学苏州大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>

Extended longevity of termite kings and queens isaccompanied by extranuclear localization of telomerase insomatic organs and caste-speciﬁc expression of its isoforms: 《Insect Science》2025年第2期364-384,共21页Marie Pangrácová Jan Krivánek Markéta Vrchotová Hana Sehadová Romana Hadravová Robert Hanus Ondrej Lukšan; supported by the Charles University Grant Agency(project GA UK No 338021);the Institute of Organic Chemistry and Biochemistry,CAS(RVO:61388963).; Kings and queens of termites are endowed with an extraordinary longevity coupled with lifelong fecundity.We recently reported that termite kings and queens dis-play a dramatically increased enzymatic activity and abun...; 关键词：alternative splicing ISOPTERA LONGEVITY TELOMERASE TERMITES TERT

Chitosan capped-NLCs enhanced codelivery of gefitinib and simvastatin into MDR HCC:impact of compositions on cell death,JNK3,and Telomerase: 《Oncology Research》2025年第2期477-492,共16页GAMALELDIN I.HARISA RIYAD F.ALZHRANI ABDULRAHMAN A.ALLUHAIDAN SULTAN M.ALAMRI AHMED H.BAKHEIT HANADI H.ASIRI SABRY M.ATTIA; Support Project(RSPD2024R1037),King Saud University,Riyadh,Saudi Arabia.; Background:Hepatocellular carcinoma(HCC)is a health problem due to multi-drug resistance(MDR).Codelivery of multiple oncotherapy in one cargo as chimeric cancer therapy(CCT)is suggested as a solution for MDR.This stud...; 关键词：Codelivery Chimeric therapy Hepatocellular carcinoma Multi-drug resistance TELOMERASE

Anti-aging based on stem cell therapy:A scoping review: 《World Journal of Experimental Medicine》2024年第3期57-63,共7页Nassar El Assaad Alain Chebly Rawad Salame Robert Achkar Nour Bou Atme Khalil Akouch Paul Rafoul Colette Hanna Samer Abou Zeid Marwan Ghosn Charbel Khalil; Stem cells are present in the tissues and organs and remain in a quiescent and undifferentiated state until it is physiologically necessary to produce new descendant cells.Due to their multipotency property,mesenchyma...; 关键词：Mesenchymal stem cell ANTI-AGING TELOMERASE Regenerative medicine Stem cell therapy

Telomerase-related advances in hepatocellular carcinoma:A bibliometric and visual analysis被引量：3: 《World Journal of Gastroenterology》2024年第9期1224-1236,共13页Hai-Yang Li Lin-Lin Zheng Nan Hu Zhi-Hao Wang Chang-Cheng Tao Ya-Ru Wang Yue Liu Zulihumaer Aizimuaji Hong-Wei Wang Rui-Qi Zheng Ting Xiao Wei-Qi Rong; the Beijing Hope Run Special Fund of Cancer Foundation of China,No.LC2020L05.; BACKGROUND As a critical early event in hepatocellular carcinogenesis,telomerase activation might be a promising and critical biomarker for hepatocellular carcinoma(HCC)patients,and its function in the genesis and tre...; 关键词：TELOMERASE Bibliometric analysis Telomerase reverse transcriptase PROGNOSIS Treatment Hepatocellular carcinoma

Construction of MTX-CS-TMP-NPs Nano-drug Delivery System and its Observation on Telomerase Activity of Cervical Cancer Hela Cells: 《Chinese Journal of Biomedical Engineering(English Edition)》2024年第1期27-32,39,共7页YAN Xiao-shuai LUO Chao YANG Fang; Objective:To construct methotrexate(MTX)-chitosan(CS)-chuanxiongmuizine(TMP)nano-delivery system MTX-CS-TMP-NPs,and to investigate its effect on the telomerase activity of cervical cancer Hela cells.Methods:MTX-CS and...; 关键词：cervical cancer(CC) Docetaxel MTX TELOMERASE nano-drug delivery system cell cycle

Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere damage repair: 《Journal of Molecular Cell Biology》2024年第3期46-60,共15页Katrina N.Estep John W.Tobias Rafael J.Fernandez Brinley M.Beveridge F.Brad Johnson; supported by the NIH(R01HL148821 and F31CA260918);University of Pennsylvania Abramson Cancer Center(Patel Scholar Award);Pennsylvania Department of Health(Health Research Formula Fund).; Although mechanisms of telomere protection are well-defined in differentiated cells,how stem cells sense and respond to telomere dysfunction,in particular telomeric double-strand breaks(DSBs),is poorly characterized.H...; 关键词：TELOMERES TELOMERASE alternative lengthening of telomeres pluripotent stem cells DNA damage double-strand breaks

Gene polymorphisms associated with sudden decreases in heart rate during extensive peritoneal lavage with distilled water after gastrectomy被引量：1: 《World Journal of Gastrointestinal Surgery》2023年第10期2154-2170,共17页Shuang Yao Yan Yuan Jun Zhang Yang Yu Guang-Hua Luo; Changzhou Sci and Tech Program,No.CJ20210113;Changzhou Health Young Talents Plan,No.CZQM2021006.; BACKGROUND Our previous study found that the telomerase-associated protein 1(TEP1,rs938886 and rs1713449)and homo sapiens RecQ like helicase 5(RECQL5,rs820196)single nucleotide polymorphisms(SNPs)were associated with ...; 关键词：Homo sapiens RecQ like helicase 5 Telomerase-associated protein 1 Polymorphism Peritoneal lavage Heart rate variability Two-dimensional polymerase chain reaction

Telomerase-mediated immortalization of human vaginal wall fibroblasts derived from patients with pelvic organ prolapse: 《Chinese Medical Journal》2023年第5期578-587,共10页Tao Guo Ting Xie Jinghe Lang Zhijing Sun; National Natural Science Foundation of China(No.81971366);Beijing Natural Science Foundation(No.Z190021);CAMS Innovation Fund for Medical Sciences(No.CIFMS 2020-I2M-C&T-B-043); Background: Extracellular matrix (ECM) remodeling is the most important pathomechanism of pelvic organ prolapse (POP). Fibroblasts are the key to ECM regulation. The passaging capacity of human vaginal wall fibroblast...; 关键词：Pelvic organ prolapse FIBROBLASTS Telomere shortening Cellular senescence

Telomerase enzyme in aging and cancer: 《Aging Communications》2022年第4期26-29,共4页Cagri Baris Gunec; Telomerase is an enzyme that maintains the length of telomeres at the ends of chromosomes.Telomeres are protective caps at the ends of chromosomes that keep genetic information intact,enable cells to multiply and prov...; 关键词：TELOMERASE ageing CANCER TELOMERES chromosomes DNA OXIDANTS glycation

Telomerase and neurons:an unusual relationship被引量：1: 《Neural Regeneration Research》2022年第11期2364-2367,共4页Gabriele Saretzki; Most people associate the enzyme telomerase with its role in maintaining telomeres,which is its best-known canonical role.For this important function,two main components are required:the protein telomerase reve rse tr...; 关键词：AUTOPHAGY brain NEURONS NEURODEGENERATION TELOMERASE TERT protein

TELOMERASE