PP2A

作品数：164被引量：417H指数：10
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相关作者：陈雯林育纯林忠宁陈慧峰林丽娜更多>>
相关机构：华中科技大学中山大学南京医科大学湖南师范大学更多>>
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相关基金：国家自然科学基金湖北省自然科学基金国家教育部博士点基金广东省自然科学基金更多>>
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The repression of oncoprotein SET by the tumor suppressor p53 reveals a p53-SET-PP2A feedback loop for cancer therapy被引量：1
《Science China(Life Sciences)》2023年第1期81-93,共13页Han Yao Wenbin Xu Yajing Liu Zhijie Cao Jia Wen Mi Zhang Zhen Wu Xiaojun Yan Zishan Jiao Zijing Zhang Jianyuan Chen Meng Zhang Wei-Guo Zhu Donglai Wang 
supported by Beijing Municipal Natural Science Foundation(7192126);the National Natural Science Foundation of China(81872311,82073132,82122054,and 81720108027);the National Key R&D Program of China(2019YFC1005200,and 2019YFC1005201);CAMS Innovation Fund for Medical Sciences(2021-I2M-1-016)。
The oncoprotein SET is frequently overexpressed in many types of tumors and contributes to malignant initiation and progression through multiple mechanisms,including the hijacking of the tumor suppressors p53 and PP2A...
关键词：P53 SET PP2A FTY720 feedback loop tumor suppression 
Molecular cloning and differential expression patterns of the regulatory subunit B' gene of PP2A in goldfish,Carassius auratus被引量：4
《Science China(Life Sciences)》2009年第8期724-732,共9页LI David WanCheng 
Supported by US NIH GRANT 1R01 EY 015765;the Changjiang Scholar Team Award (Grant No. IRT0045);Fu-rong Scholar Professorship Funds (Grant No. 24030604)
It is well established that the protein serine/threonine phosphatase 2A(PP2A) plays very important roles in many different cellular processes,including cell proliferation and differentiation,gene expression,neurotrans...
关键词：PP2A Protein DEPHOSPHORYLATION PP2A-B’δ regulatory subunit. 
Assembly and structure of protein phosphatase 2A被引量：13
《Science China(Life Sciences)》2009年第2期135-146,共12页SHI Yi Gong Center for Structural Biology, Department of Biological Sciences and Biotechnology, and School of Medicine, Tsinghua University, Beijing 100084, China 
Supported by NIH grant R01 CA123155;Start-up Funds from Tsinghua Univer-sity
Protein phosphatase 2A (PP2A) represents a conserved family of important protein serine/threonine phosphatases in species ranging from yeast to human. The PP2A core enzyme comprises a scaffold subunit and a catalytic ...
关键词：PROTEIN PHOSPHORYLATION DEPHOSPHORYLATION PP2A STRUCTURE mechanism 
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