OBJECTIVE PP2Ac demethyl⁃ation is regulated by LCMT(a specific leucine carboxyl methyltransferase catalyzing methyla⁃tion of PP2A)and PME(a specific methylester⁃ase catalyzing demethylation of PP2A.This study was to i...
The project supported by National Natural Science Foundation of China(81274120,81273498);the Beijing Natural Science Foundation(7132110);the Beijing Science and Technology Program(Z131102002813066);the Capital Health Development Scientific Grant(2011-1001-05)
OBJECTIVE The aim of the present study was to investigate the effect of cornel iridoid glycoside(CIG)on tau hyperphosphorylation induced by wortmannin(WT)and GF-109203X(GFX)and the underlying mechanisms.METHODS Human ...