supported by the National Key Research and Development Program of China (2016YFC1306300);the National Basic Research Program of China (2013CB530850);funds from Beijing Normal University (11100704, 10300-310421102)
Dear Editor,Fact one of the current research on protein-protein interactions is that tagging is widely used.Tagging is a good way to track or visualize a protein.Researchers assume that tagging does not change the str...
supported by the National High Technology Research and Development Program of China(2012AA020201);National Basic Research Program of China(2013CB910802,2010CB912700);International Science&Technology Cooperation Program of China(2014DFB30020);National Natural Science Foundation of China(31000379,31000587,31000591);Chinese State Key Project Specialized for Infectious Diseases(2012ZX10002012-006)
Integration of pathway and protein-protein interaction(PPI) data can provide more information that could lead to new biological insights. PPIs are usually represented by a simple binary model, whereas pathways are rep...
supported in part by the National Natural Science Foundation of China (Grant Nos. 30770498, 30625012 and 60721003);the National High-Tech Research and Development Program of China (Grant No.2006AA020403);the National Basic Research Program of China (Grant No.2009CB918801)
The interaction strength between 2 proteins is not constant but variable under different conditions. For a given biological process, identification of protein-protein interactions (PPIs) undergoing dynamic change in i...
supported by the National Basic Research Program of China (Grant No.2006CB500702);the Shanghai Lead-ing Academic Discipline Project (Grant No.J50103);Shanghai University Systems Biology Reasearch Funding (GrantNo.SBR08001)
Alpha-synuclein plays an important role in Parkinson's disease(PD).The current study of alpha-synuclein mainly concentrates at the gene level.However, it is found that the study at the protein level has special signif...