supported by grants from the National Basic Research Program (973 Program) (Grant No. 2011CB944100and 2011CB944101);National Natural Science Foundation of China (Grant No. 90919024);the Special Foundation Work Program, the Ministry of Science and Technology (Grant No.2009FY120100);the "100-Talent Program" of Chinese Academy of Sciences (Grant No. Y1SLXb1365);the National Programs for High Technology Research and Development(863 Program;Grant No. 2012AA020409) by the Ministry of Science and Technology of China
In the RNA world, RNA is assumed to be the dominant macromolecule performing most, if not all, core "house-keeping" functions. The ribo-cell hypothesis suggests that the genetic code and the translation machinery ma...
supported by grants from Knowledge Innovation Program of the Chinese Academy of Sciences(Grant No.KSCX2-EW-R-01-04);Natural Science Foundation of China(Grant No.90919024 and 30900831);the Ministry of Science and Technology of China as the National Science and Technology Key Project (Grant No.2008ZX10004-013);the Special Foundation Work Program(Grant No.2009FY120100);the National Basic Research Program(Grant No. 2011CB944100)
Although strand-biased gene distribution (SGD) was described some two decades ago, the underlying molecular mechanisms and their relationship remain elusive. Its facets include, but are not limited to, the degree of...
supported by a faculty fund from King Abdullah University of Science and Technology (http://www.kaust.edu.sa) awarded to JY
The organization of the canonical genetic code needs to be thoroughly illuminated. Here we reorder the four nu- cleotides--adenine, thymine, guanine and cytosine--according to their emergence in evolution, and apply t...
The codon table for the canonical genetic code can be rearranged in such a way that the code is divided into four quarters and two halves according to the variability of their GC and purine contents, respectively. For...