supported by a Grant-in-Aid for Scientific Research(B)JP21H02808(to TM);JST SPRING JPMJSP2136(to MI)。
Neural stem cells(NSCs)are the source of all neurons and glial cells(astrocytes and oligodendrocytes)in the central nervous system.The adult mammalian brain retains NSCs in the subgranular zone of the dentate gyrus in...
National Eye Institute R01-EY024519 and U01-EY027267(to DRH);the Center for Zebrafish Research,University of Notre Dame.
Retinal damage in the adult zebrafish induces Müller glia reprogramming to produce neuronal progenitor cells that proliferate and differentiate into retinal neurons.Notch signaling,which is a fundamental mechanism kn...