supported by the National Natural Science Foundation of China(No.82104289);the Yuandu Scholar Grant of Weifang City(Shandong,China)to JJL;the Shandong Provincial Health Commission of China(No.M2022053)。
Genetic mutations in TP53 contribute to human malignancies through various means.To date,there have been a variety of therapeutic strategies targeting p53,including gene therapy to restore normal p53 function,mutant p...
Objective To explore the possible mechanism of rAd-p53 involved in glucose metabolism by observing the different effects of rAd-p53 on high-fat diet(HFD)fed with low-dose streptozotocin(STZ)treated(HFD/STZ)mice(β-cel...