SIGNAL_TRANSDUCTION

作品数：482被引量：3037H指数：28
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Targeting TGFβ signal transduction for cancer therapy被引量：25
《Signal Transduction and Targeted Therapy》2021年第2期277-296,共20页Sijia Liu Jiang Ren Peter ten Dijke 
We apologize to authors whose papers could not be cited due to space limitations.We are grateful to Dieuwke Marvin and Adilson Fonseca Teixeira for a critical reading and comments.We thank Gerard van der Zon for the immunofluorescent staining images of NMuMG cells.Research on targeting TGFβ for cancer therapy in our laboratory is supported by the Cancer Genomics Centre Netherlands。
Transforming growth factor-β(TGFβ) family members are structurally and functionally related cytokines that have diverse effects on the regulation of cell fate during embryonic development and in the maintenance of a...
关键词：TGFΒ HOMEOSTASIS STIMULATION 
Wnt and BMP signaling crosstalk in regulating dental stem cells:Implications in dental tissue engineering被引量：19
《Genes & Diseases》2016年第4期263-276,共14页Fugui Zhang Jinlin Song Hongmei Zhang Enyi Huang Dongzhe Song Viktor Tollemar Jing Wang Jinhua Wang Maryam Mohammed Qiang Wei Jiaming Fan Junyi Liao Yulong Zou Feng Liu Xue Hu Xiangyang Qu Liqun Chen Xinyi Yu Hue H.Luu Michael J.Lee Tong-Chuan He Ping Ji 
The authors apologize to those investigators whose original work was not cited due to space constraints.The authors’research was supported in part by research grants from the National Institutes of Health(AT004418&AR054381 to TCH&HHL);Scoliosis Research Society(MJL&TCH),the 973 Program of Ministry of Science and Technology(MOST)of China(#2011CB707900 to TCH),the National Natural Science Foundation of China(#81400493 to FZ);Chongqing Municipal Commissions on Education(#KJ130303 to JW);Chongqing Municipal Commissions on Science&Technology(#cstc2013jcyjA0093 to JW);Chongqing Municipal Commissions Yubei District Science&Technology(#2014 Society of Human Resource Unit 14 to JW).MKM was a recipient of Howard Hughes Medical Institute Medical Research Fellowship.
Tooth is a complex hard tissue organ and consists of multiple cell types that are regulated by important signaling pathways such as Wnt and BMP signaling.Serious injuries and/or loss of tooth or periodontal tissues ma...
关键词：BMP signaling Dental stem cells Oral stem cells Regenerative dentistry Signal transduction Tissue engineering Wnt signaling 
Regulation of TGF-β signaling by Smad7被引量：49
《Acta Biochimica et Biophysica Sinica》2009年第4期263-272,共10页Xiaohua Yan Ziying Liu Yeguang Chen 
Acknowledgements The authors wish to apologize to the investigators whose outstanding work was not cited here because of space limitation. The authors would also like to thank Mr Martin Ting Ma for assisting in manuscript preparation.;Funding This work was supported by the grants from the National Natural Science Foundation of China （30430360, 30671033, and 30600096）, the Major State Basic Research Development Program of China （2004CB720002, 2006CB943401, and 2006CB910102）, and the National High Technology Research and Development Program of China （2006AA02Z 172）.
Transforming growth factor （TGF）-β is a pleiotropic cytokine regulating a variety of cellular processes such as cell growth, differentiation, apoptosis, migration, cell adhesion, and immune response. In the well-un...
关键词：TGF-Β signal transduction SMAD7 feedback loop CROSSTALK 
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