SYSTEMS_BIOLOGY

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Gene regulatory network stabilized by pervasive weak repressions: micro RNA functions revealed by the May–Wigner theory被引量：3
《National Science Review》2019年第6期1176-1188,共13页Yuxin Chen Yang Shen Pei Lin Ding Tong Yixin Zhao Stefano Allesina Xu Shen Chung-I Wu 
supported by the National Natural Science Foundation of China(31730046 and 91731301);the National Basic Research Program(973 Program)of China(2014CB542006);the 985 Project(33000–18841204);National Institute of Health,USA(5 R01 GM058686-09 to WU,Chung-I)
Food web and gene regulatory networks(GRNs)are large biological networks,both of which can be analyzed using the May-Wigner theory.According to the theory,networks as large as mammalian GRNs would require dedicated ge...
关键词：micro RNAs network stability CANALIZATION May-Wigner theory systems biology RNA crosstalk 
A primer on recent developments in cancer immunotherapy, with a focus on neoantigen vaccines被引量：1
《Journal of Cancer Metastasis and Treatment》2018年第1期10-33,共24页Taku A.Tokuyasu Jian-Dong Huang 
This work was supported by a National Basic Research Program of China(973 Program,No.2014CB745202);the Shenzhen Peacock Team Project(No.KQTD2015033117210153);the Shenzhen Science and Technology Innovation Committee Basic Science Research Grants(No.JCYJ20170413154523577,No.JCYJ20150629151046896);the Guangdong Natural Science Funds for Distinguished Young Scholar Grant(No.S2013050016987).
Cancer immunotherapy has now been conclusively shown to be capable of producing durable responses for a substantial number of patients.Adoptive cell transfer and checkpoint blockade therapies in particular both demons...
关键词：IMMUNOTHERAPY cancer vaccine IMMUNOINFORMATICS precision medicine combination therapy theoretical models systems biology 
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