TENOFOVIR

作品数:131被引量:481H指数:13
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相关领域:医药卫生更多>>
相关作者:张仁芳洪泠李玮叶春艳赵英仁更多>>
相关机构:上海市公共卫生临床中心成都学院(成都大学)四川抗菌素工业研究所浙江大学医学院附属邵逸夫医院常州市第三人民医院更多>>
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相关基金:国家自然科学基金北京市自然科学基金瑞士科学基金更多>>
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Tenofovir amibufenamide:A potential alternative for chronic hepatitis B treatment
《World Journal of Gastroenterology》2025年第10期139-143,共5页Hai-Nan Ma Kai-Sen Cao Yan-Miao Liu Cheng Chen Hang Zhang Fu-Shan Tang 
Tenofovir amibufenamide(TMF)is a novel prodrug of tenofovir that demonstrates a promising safety and efficacy profile.A recent study by Peng et al compared TMF with tenofovir alafenamide in the treatment of chronic he...
关键词:Tenofovir amibufenamide Tenofovir alafenamide Chronic hepatitis B Antiviral efficacy Safety profile HYPERLIPIDEMIA 
Factors Associated with Chronic Kidney Disease in Patients Living with HIV in Yamoussoukro (Ivory Coast)
《Open Journal of Nephrology》2024年第4期564-573,共10页Koffi Christ Ziahy Reine-Marie Yao Ahua Sébastienne Gnohité Grâce Kpan Kéhi Jonathan Gonan Abdoul Yanick Affi Mélèdje Césaire Wognin Manzan Anastasie Tia Weu Mélanie Ouattara Bourhaïma 
Introduction: Human immunodeficiency virus (HIV) infection is an epidemic in sub-Saharan Africa and is a risk factor for kidney disease. The aim of this study was to assess the prevalence of chronic kidney disease (CK...
关键词:HIV Chronic Kidney Disease SCREENING TENOFOVIR 
Long-term efficacy and safety of tenofovir alafenamide,tenofovir disoproxil fumarate,and entecavir in treating hepatitis B virus-related acute-on-chronic liver failure:A 144-week data analysis
《Liver Research》2024年第4期295-303,共9页Yeqiong Zhang Wenxiong Xu Zhexuan Deng Lu Wang Xingrong Zheng Xiang Zhu Xuejun Li Jianguo Li Xin Shu Jing Lai Liang Peng Chan Xie 
supported by grants from Key-Area Research and Development Program of Guangdong Province(No.2020B0101130015);Guangdong Medical Science and Technology Research Fund(No.A2021304);the Natural Science Foundation of China(No.82070611);Guangzhou Science and Technology Plan Projects(No.2023B03J1287);Guangzhou Science and Technology Program Key Projects(No.2023B01J1007);Sun Yat-Sen University Clinical Research 5010 Program(No.2020007);the Five-Year Plan of Third Affiliated Hospital of Sun Yat-sen University(No.2023W106);Clinical trial number:ClinicalTrials.gov ID:NCT03920618.
Background and aims:Antiviral therapy is essential for hepatitis B virus-related acute-on-chronic liver failure(HBV-ACLF).No data are available on the long-term prognosis or safety of tenofovir alafenamide(TAF),tenofo...
关键词:Tenofovir alafenamide(TAF) Tenofovir disoproxil fumarate(TDF) Entecavir(ETV) Hepatitis B virus(HBV) Acute-on-chronic liver failure(ACLF) 
Anti-hepatitis B Virus Treatment with Tenofovir Amibufenamide Has No Impact on Blood Lipids: A Real-world, Prospective, 48-week Follow-up Study
《Journal of Clinical and Translational Hepatology》2024年第12期997-1008,共12页Yue Chen Wenkang Gao Huikuan Chu Afnan Ahmed Mohamed Al-Asbahi Shengqi Yan Hang Yuan Jiake Che Zilu Cheng Zexuan Li Jin Ye Rong Lin Xiaohua Hou Fan Du Ling Yang 
funded by the National Natural Science Foundation of China[82270614,81974078,81570530,and 81370550 to LY,82000561to HC];the National Key R&D Program of China[2023YFC2413804 to LY and 2022YFA1305600 to HC];the Science Foundation of Hubei Province[2019ACA133 to LY]and the Science Foundation of Union Hospital[2021xhyn005]to HC.
Background and Aims:The effect of tenofovir amibufenamide(TMF)on blood lipid profiles in patients with chronic hepatitis B(CHB)remains unclear.This study aimed to explore whether TMF affects blood lipids during 48 wee...
关键词:Tenofovir amibufenamide Antiviral treatment Chronic hepatitis B Blood lipid Virological response Palmitic acid 
Effectiveness of switching to bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed people with HIV with historical drug resistance mutations
《Chinese Medical Journal》2024年第22期2758-2760,共3页Ziwei Chang Hongyan Zhu Yiting Zhang Yaling Chen Jiahui Li Jiamin Qin Yueping Zhu Hongxia Wei Yongfeng Yang Meiyin Zou Feng Qian Zhiliang Hu 
This study was funded in part by the project of Nanjing Infectious Disease Clinical Medical Center and the project of Innovation center for infectious disease of Jiangsu Province(NO.CXZX202232);the Jiangsu Provincial Health Commission Medical Research Foundation(No.M2022030);the Nanjing Medical Science and Technique Development Foundation(No.ZKX21037);the Research Project of Nantong Municipal Health Commission(No.MS2023077).
To the Editor:China provides free antiretroviral therapy(ART)for people with human immunodeficiency virus(HIV),typically using two nucleoside reverse transcriptase inhibitors(NRTIs)and one non-nucleoside reverse trans...
关键词:mortality REGIMEN resistance 
Differences of Efficacy Between Tenofovir Alafenamide Fumarate and Tenofovir Disoproxil Fumarate in Pregnant Women With Different Hepatitis B Virus DNA Loads
《Infectious Microbes & Diseases》2024年第3期134-140,共7页Chengjing Tao Guanlun Zhou Hongxiu Jiang Chao Chen Yuhao Ju Xingran Tao Ping Zhang Shuorong Liu Guorong Han 
supported by the Key Project of Hangzhou Science and Technology Bureau of Agriculture and Social Development Scientific Research(2022A04A02);Zhejiang Province Medical and Health Research Project(2018KY628);Hangzhou City Social Development Scientific Research Active Design Project(20172016A03).
Tenofovir alafenamide fumarate(TAF)has been endorsed by guidelines for blockade ofmother-to-child transmission of hepatitis B virus(HBV),given that its efficacy and safety are comparable to tenofovir disoproxil fumara...
关键词:hepatitis B virus tenofovir alafenamide fumarate tenofovir disoproxil fumara HBeAg positive HBV DNA 
Clinical efficacy and safety of bictegravir/emtricitabine/tenofovir alafenamide and lamivudine/dolutegravir in the treatment-naive patients with acquired immunodeficiency syndrome
《China Medical Abstracts(Internal Medicine)》2024年第3期157-157,共1页WANG Jiangrong 
Objective To analyze the efficacy and safety of integrase inhibitor-based single-tablet regimens bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) and lamivudine/dolutegravir (3TC/DTG) in the treatment-naive p...
关键词:PATIENTS immunodeficiency TREATMENT 
Improvement of hepatic fibrosis after tenofovir disoproxil fumarate switching to tenofovir alafenamide for three years
《World Journal of Hepatology》2024年第7期1009-1017,共9页Tung Huynh Delana MyAn Bui Tina Xiwen Zhou Ke-Qin Hu 
BACKGROUND Both tenofovir alafenamide(TAF)and tenofovir disoproxil fumarate(TDF)are the first-line treatments for chronic hepatitis B(CHB).We have showed switching from TDF to TAF for 96 weeks resulted in further alan...
关键词:Tenofovir alafenamide Tenofovir disoproxil fumarate SWITCHING Hepatic fibrosis improvement Aspartate aminotransferase to platelet ratio index Fibrosis-4 Shear wave elastography 
Effectiveness and safety of tenofovir amibufenamide in chronic hepatitis B patients被引量:3
《World Journal of Gastroenterology》2024年第26期3261-3263,共3页Li-Yang Meng Chao-Ting Yang Jian-Feng Bao Jin-Song Huang 
Supported by Biomedical Enterprise Project of Hangzhou Science and Technology Bureau,No.2021WJCY061 and No.2022WJC230.
This letter to the editor relates to the study entitled“Tenofovir amibufenamide vs tenofovir alafenamide for treating chronic hepatitis B:A real-world study”,which was recently published by Peng et al.Hepatitis B vi...
关键词:Tenofovir amibufenamide Chronic hepatitis B Non-alcoholic fatty liver disease Alanine transaminase normalization Virological response 
Changes in blood lipid levels and influencing factors among treatment-naïve adult male HlV/AlDS patients following BlC/FTC/TAF vs.3TC+EFV+TDF
《Chinese Medical Journal》2024年第12期1447-1452,共6页Xi Wang An Liu Zaicun Li Hongwei Zhang Ruojun Esther Wu Ying Shao Jianwei Li Jiangzhu Ye Wei Liu Lijun Sun 
supported by the Gilead Sciences and the Capital Health Research and Development of Special Fund(No.2022-1G-3015)
Background:Antiretroviral therapy(ART)was often associated with dyslipidemia among human immunodeficiency virus(HIV)/acquired immunodeficiency syndrome(AIDS)patients.This study aimed to assess treatment-naïve adult ma...
关键词:Antiretroviral therapy Blood lipids Bictegravir/emtricitabine/tenofovir alafenamide Lamivudine efavirenz and tenofovir disoproxil fumarate BIC/FTC/TAF 3TC+EFV+TDF HIV AIDS 
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