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Targeting the MYCN-MDM2 pathways for cancer therapy:Are they druggable?: 《Genes & Diseases》2025年第2期271-287,共17页Wei Wang Yi Du Sayantap Datta Josef F.Fowler Hannah T.Sang Najah Aibadari Wei Li Jennifer Foster Ruiwen Zhang; supported by the National Institutes of Health (NIH)/National Cancer Institute (No.R01CA214019 to RZ);support was provided by the NCl grant R01CA240447 to WL.; Targeting oncogenes and their interactive partners is an effective approach to developing novel targeted therapies for cancer and other chronic diseases.We and others have long suggested the MDM2 oncogene being an exc...; 关键词：MDM2 MYCN NEUROBLASTOMA Signaling pathway Targeted therapy

When you need them,they are not there:hedge capacities of cryptocurrencies disappear in downtrend markets: 《Financial Innovation》2024年第1期1185-1222,共38页Ahmed Bossman Mariya Gubareva Samuel Kwaku Agyei Xuan Vinh Vo; Fundacão para a Ciencia e a Tecnologia(Grant No.UIDB/04521/2020).; We provide empirical evidence supporting the economic reasoning behind the impossibility of diversification benefits and the hedge attributes of cryptocurrencies remaining in force during the downside trends observed ...; 关键词：Stablecoins Stocks Cryptocurrencies Bitcoin US treasuries Digital financial market Conventional financial market Flight-to-cryptosafety Flight-to-safety TVP-VAR model

What are they considering when they face a fetus with birth defects?A qualitative study on ethical attitudes of health professionals in China: 《Global Health Research and Policy》2024年第1期329-340,共12页Yanlin Liu Xiaomin Wang Junqun Fang Wei Zhou Dan Luo; Major Scientific and Technological Projects for collaborative prevention and control of birth defects in Hunan Province(2019SK1011).; Background Birth defects are the leading cause of mortality in newborn babies and children under five years old.In response,the Chinese government has implemented a three-tiered prevention strategy,which has brought e...; 关键词：Birth defects China Health professionals PERSPECTIVES Qualitative study

That’s What They Say About the Supply Chain!: 《China's Foreign Trade》2024年第6期15-17,共3页Wan Zewei Zhao Ailing Ma Xiaoyue; The 2nd China International Supply Chain Expo(CISCE),had been the focus of international attention.Delegations from more than 100 countries and international organizations came to the expo,either participating by exhi...; 关键词：Supply CHAIN PARTNER

Assessing the Financial Impact of Physician Self-Referral on Patients and How They Coped with Payment in South-Eastern Nigeria: 《Health》2024年第12期1250-1267,共18页Bartholomew Eze Jones Mari Okebaram Chukwudi Amaugo Lucky Kyaruzi Imani; Background: Dual practice occurs where healthcare professionals, particularly medical doctors, engage in concurrent public and private clinical work for remuneration. This practice can impact financial burden on patie...; 关键词：Physician Self-Referral Private Practice Dual Practice Financial Impact

A Safer World for Children Defending children from the many dangers they face: 《空中英语教室（中级版）》2024年第12期29-31,51,52,56,共6页Elizabeth Koroma; All humans areborn small,weak and completely dependent on others,and it takes years for them to become self-reliant.This means that children rely on adultsto provide for them and protect them,and they face great dange...; 关键词：CHILDREN THEY ADULT

What Do They Look Like?: 《空中英语教室（初级版．大家说英语）》2024年第12期45-47,56,共4页Maria Chiu; You can describe a person in many ways.They may be young or old.You can talk about their height.They may be tall,short or average.You can talk about their hair,too.It can be long or short,curly or straight.It may be b...; 关键词：BLACK STRAIGHT DAYS

Quran memorisation and heart rate variability:How do they correlate?: 《World Journal of Clinical Cases》2024年第29期6275-6284,共10页Ahmad Rohi Ghazali Nor Malia Abd Warif Noor Anisah A Yazit Norsham Juliana Ismarulyusda Ishak Farah Wahida Ibrahim Arimi Fitri Mat Ludin Dzalani Harun Santibuana Abd Rahman Wan Nor Atikah Che Wan Mohd Rozali; Supported by the Research Grant from Universiti Kebangsaan Malaysia,No.GGP-2017-061.; BACKGROUND Heart rate variability(HRV)was shown to be affected by performing religious activities.AIM To examine the relationship between the level of Quran(the holy book of Muslims)memorisation and HRV among teenager...; 关键词：Heart rate variability Autonomic nervous system Quran memorisation Tahfiz student HEARTBEAT

新课程理念下小学英语作业创新设计——以Unit 5 What do they do?Story time板块为例: 《英语教师》2024年第20期155-157,共3页陆紫嫣; 基于新课程理念,以译林版小学《英语》五年级(上)Unit 5 What do they do? Story time板块为例,对创新小学英语课后作业设计的路径作出了积极思考和案例分析,集中体现在,寓教于乐,融入游戏,设计学习理解类作业;关联生活,打造情境,设计...; 关键词：新课程理念小学英语英语教学作业设计

Humans Are Going to the Moon's South Pole.This Is How They'll Drive There: 《中国战略新兴产业》2024年第9期91-91,共1页无; NASA计划在2030年通过Artemis V任务将两名宇航员送往月球南极进行为期六天的科学实验。为此,NASA委托设计了一种能够在月球极端条件下使用的月球地形车(LTV)。Goodyear、Michelin和Venturi Astrolab三家公司正在研究适合月球环境的轮...; 关键词：月球土壤月球环境极端温度极端条件轮胎设计月球地形太阳辐射科学实验

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