Gastrointestinal stromal tumors(GISTs)are the most common mesenchymal tumors of the gastrointestinal tract,driven by mutations in the proto-oncogene c-KIT or platelet-derived growth factor alpha(PDGFRA)gene in 85%-90%...
supported by Sichuan Province Central Government Guide Local Science and Technology Development Project(No.2023ZYD0169).
Background:Non-small cell lung cancer(NSCLC)is often accompanied by brain metastasis(BM),and the prognosis of patients with BM is poor.This study assesses the prognostic impact of BM in NSCLC patients with epidermal g...
supported in part by grants from the National Natural Science Foundation of China(Nos.82102859,82272875 and 12126605);Shanghai Rising-Star Program(Nos.23QA1408000 and 22QA1407800);Shanghai Science and Technology Innovation Action Plan Medical Innovation Research Program(Nos.23Y11904100 and 21Y11913600);the Health and Family Planning Commission of Shanghai Municipality(No.20224Y0067);Ningbo Top Medical and Health Research Program(No.2022030208);Shanghai Nature Foundation Project(No.21ZR1453200);National Key Clinical Specialty Construction Project,Original exploration project of Shanghai Natural Science Foundation(No.23ZR1480600);Shanghai“Rising Stars of Medical Talent”Youth Development Program Youth Medical Talents-Specialist Program.
Although third-generation Epidermal growth factor receptor—tyrosine kinase inhibitors(EGFR-TKI)is standard of care for patients with EGFR-mutant Non-small cell lung cancer(NSCLC),little is known about the predictors ...