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作品数:701被引量:3400H指数:25
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Oncoprotein HBXIP induces PKM2 via transcription factor E2F1 to promote cell proliferation in ER-positive breast cancer被引量:4
《Acta Pharmacologica Sinica》2019年第4期530-538,共9页Bo-wen Liu Tiarvjiao Wang Lei-lei Li Lu Zhang Yun-xia Liu Jin-yan Feng Yue Wu Fei-fei Xu Quan-sheng Zhang Ming-zhu Bao Wei-ying Zhang Li-hong Ye 
National Basic Research Program of China (973 Program, No. 2015CB553905);National Natural Science Foundation of China (Nos. 81372186 and 31670771);the Fundamental Research Funds for the Central Universities;Project of Prevention and Control of Key Chronic Non Infectious Diseases (No. 2016YFC1303401).
We have reported that hepatitis B X-interacting protein (HBXIP, also termed LAMT0R5) can act as an oncogenic transcriptional co-activator to modulate gene expression, promoting breast cancer development. Pyruvate kina...
关键词:HBXIP PKM2 E2F1 BREAST cancer proliferation 
Hepatitis B virus X protein promotes human hepatoma cell growth via upregulation of transcription factor AP2α and sphingosine kinase 1被引量:5
《Acta Pharmacologica Sinica》2015年第10期1228-1236,共9页Zhan-ping LU Ze-lin XIAO Zhe YANG Jiong LI Guo-xing FENG Fu-quan CHEN Ying-hui LI Jin-yan FENG Yu-en GAO Li-hong YE Xiao-dong ZHANG 
Acknowledgements This work was supported by grants from the National Basic Research Program of China (973 Program, No 2015CB553703, 2015CB553905), the National Natural Science Foundation of China (No 81272218, 81372186) and the Project of Prevention and Treatment of Key Infectious Diseases (No 2014ZX0002002005).
Aim: Sphingosine kinase 1 (SPHK1) is involved in various cellular functions, including cell growth, migration, apoptosis, cytoskeleton architecture and calcium homoeostasis, etc. As an oncogenic kinase, SPHK1 is as...
关键词:hepatitis B virus X protein hepatocellular carcinoma HepG2 ceils tumor xenograft model sphingosine kinase 1 transcription factor AP2α ceil proliferation 
Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bZIP28 in Arabidopsis被引量:13
《Science China(Life Sciences)》2015年第3期270-275,共6页SUN Le ZHANG Shuang-Shuang LU Sun-Jie LIU Jian-Xiang 
supported by grants from the National Basic Research Program of China(973 Program,2012CB910500);the National Natural Science Foundation of China(31171157,31222008);the Specialized Research Fund for the Doctoral Program of Higher Education(20130071110011)
Many sources of stress cause accumulation of unfolded or misfolded proteins in endoplasmic reticulum(ER), which elicits the unfolded protein response(UPR) to either promote cell survival or programmed cell death depen...
关键词:membrane-associated transcription factor ER stress unfolded protein response bZ IP28 S1P S2P 
Expressional Analysis of an EREBP Transcription Factor Gene OsEBP-89 in Rice被引量:6
《Acta Biochimica et Biophysica Sinica》2004年第1期21-26,共6页HuiSHEN Zong-YangWANG 
This work was supported by the grants from the High Technology Department Program of China(No.2002AA2Z1003) ; the Major State Basic Research Development Program of China (973 Program) (No. G1999011604)
OsEBP-89 gene encodes an ethylene responsive element binding protein (EREBP) transcription factor from rice (Oryza saliva). Northern blot analysis revealed that OsEBP-89 was expressed in root, stem, seeds, flowers and...
关键词:OsEBP-89 gene RICE EREBP subfamily transcription factor tissue expression 
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