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IPA1 functions as a downstream transcription factor repressed by D53 in strigolactone signaling in rice被引量：68: 《Cell Research》2017年第9期1128-1141,共14页Xiaoguang Song Zefu Lu Hong Yu Gaoneng Shao Jinsong Xiong Xiangbing Meng Yanhui Jing Guifu Liu Guosheng Xiong Jingbo Duan Xue-Feng Yao Chun-Ming Liu Hongqing Li Yonghong Wang Jiayang Li; We thank Prof Shouyi Chen （Institute of Genetics and Devel- opmental Biology, Chinese Academy of Science） for providing the plasmids GAL4BD, 35sLUC and pRTL, Prof Qian Qian and Dr Xingming Hu （State Key Laboratory of Rice Biology, China Na- tional Rice Research Institute） for providing the rice miRNA156 overexpressing lines, Prof Chuanyou Li for sharing the Plant Imaging System （Berthold Technologies）, and lab members （Drs Lei Wang, Liang Jiang, Xue Liu, Huihui Liu） for their technical assistance, and Dr Bing Wang for comments on the manuscript. We are grateful to the Genomics and Bioinformatics Facility of State Key Laboratory of Plant Genomics, Institute of Genetic and Developmental Biology for phosphor imaging. This work was supported by grants from the National Key Research and Devel- opment Program of China （Grant 2016YFD0101800）, National Natural Science Foundation of China （Grant 91635301）, and the Strategic Priority Research Program ＂Molecular Mechanism of Plant Growth and Development＂（Grant XDPB0401）.; Strigolactones （SLs）, a group of carotenoid derived terpenoid lactones, are root-to-shoot phytohormones sup- pressing shoot branching by inhibiting the outgrowth of axillary buds. DWARF 53 （D53）, the key repressor...; 关键词：TILLERING plant architecture PHYTOHORMONE protein interaction Oryza Sativa L.

Crystal structure of a TAF1-TAF7 complex in human transcription factor liD reveals a promoter binding module被引量：2: 《Cell Research》2014年第12期1433-1444,共12页Hui Wang Elizabeth C Curran Thomas R Hinds Edith H Wang Ning Zheng; The general transcription factor liD （TFIID） initiates RNA polymerase II-mediated eukaryotic transcription by nucleating pre-initiation complex formation at the core promoter of protein-encoding genes. TAF1, the lar...; 关键词：TRANSCRIPTION TFIID TAF winged helix DNA binding cell cycle progression

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system被引量：68: 《Cell Research》2013年第10期1163-1171,共9页Albert W Cheng Haoyi Wang Hui Yang Linyu Shi Yarden Katz Thorold W Theunissen Sudharshan Rangarajan Chikdu S Shivalila Daniel B Dadon Rudolf Jaenisch; Technologies allowing for specific regulation of endogenous genes are valuable for the study of gene functions and have great potential in therapeutics. We created the CRISPR-on system, a two-component transcriptional...; 关键词：CRISPR transcription factor synthetic biology gene expression artificial transcription factor

Downregulation of the transcription factor KLF4 is required for the lineage commitment of T cells被引量：2: 《Cell Research》2011年第12期1701-1710,共10页Xiaomin Wen Haifeng Liu Gang Xiao Xiaolong Liu; The roles of the reprogramming factors Oct4, Sox2, c-Myc and Klf4 in early T cell development are incompletely defined. Here, we show that Klf4 is the only reprogramming factor whose expression is downregulated when e...; 关键词：KLF4 early T cell development T cell lineage commitment

AKNA： Another AT-hook transcription factor ＂hooking-up＂ with inflammation被引量：1: 《Cell Research》2011年第11期1528-1530,共3页; Previous studies highlight a key role for AT-hook transcription factors as master regulators of fundamental cellu- lar processes involved in development, immune function, cancer, diabetes and other human diseases [1, 2].; 关键词：转录因子挂钩炎症免疫功能人类疾病纤维素糖尿病

The ATAF1 transcription factor： At the convergence point of ABA-dependent plant defense against biotic and abiotic stresses被引量：7: 《Cell Research》2009年第12期1322-1323,共2页Brigitte Mauch-Mani Victor Flors; Because of their sessile lifestyle, plants have evolved sophisticated ways of coping with the various biotic and abiotic stresses they can encounter during their life. Their defensive reactions to a given stress have ...; 关键词：植物进化非生物转录因子汇合点 ABA 信号转导通路生活方式信号途径

An R2R3-type transcription factor gene AtMYB59 regulates root growth and cell cycle progression in Arabidopsis被引量：21: 《Cell Research》2009年第11期1291-1304,共14页Rui-Ling Mu Yang-Rong Cao Yun-Feng Liu Gang Lei Hong-Feng Zou Yong Liao Hui-Wen Wang Wan-Ke Zhang Biao Ma Ji-Zhou Du Ming Yuan Jin-Song Zhang Shou-Yi Chen; MYB proteins play important roles in eukaryotic organisms. In plants, the R1R2R3-type MYB proteins function in cell cycle control. However, whether the R2R3-type MYB protein is also involved in the cell division proce...; 关键词：MYB protein transcription factor cell cycle root growth

A transcription factor with a bHLH domain regulates root hair development in rice被引量：21: 《Cell Research》2009年第11期1309-1311,共3页Wona Ding Zhiming Yu Yanli Tong Wei Huang Hanmin Chen Ping Wu; In plants, root hairs are important organs for the up- take of nutrients and water from the rhizosphere and serve as sites of interaction with soil microorganisms [ 1]. A root hair grows as an extension of a single ep...; 关键词：转录因子根毛水稻植物细胞分化调控螺旋表皮细胞微生物

WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells被引量：2: 《Cell Research》2009年第6期796-796,共1页Huiming Xu Weicheng Wang Chunliang Li Hongyao Yu Acong Yang Beibei Wang Ying Jin

WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells被引量：8: 《Cell Research》2009年第5期561-573,共13页Huiming Xu Weicheng Wang Chunliang Li Hongyao Yu Acong Yang Beibei Wang Ying Jin; Acknowledgments We are grateful to Dr DA Melton （Harvard University） for shar- ing his human ES cells with us. The study was supported by grants from the National High Technology Research and Development Program of China （2006CB943900）, the National Natural Science Foundation of China （General Program, 30500088）, the Shang- hai Jiao Tong University School of Medicine, and the Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. The study was also supported by the Shanghai Leading Academic Deciline Project （S30201）.; POU transcription factor OCT4 not only plays an essential role in maintaining the pluripotent and self-renewing state of embryonic stem （ES） cells but also acts as a cell fate determinant through a gene dosage effec...; 关键词：transcription factor OCT4 WWP2 protein degradation embryonic stem cells

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