Eukaryotic transcription begins with the assembly of general transcription factors(GTFs)including TFIID,IIA,IIB,IIE,IIF,and IIH,which help Pol II to engage with promoters.The binding of TATA-box binding protein(TBP)to...
The general transcription factor liD (TFIID) initiates RNA polymerase II-mediated eukaryotic transcription by nucleating pre-initiation complex formation at the core promoter of protein-encoding genes. TAF1, the lar...