Background: Two types of treatment are being used for patients with ruptured intracranilal aneurysms: endovascular detachable-coil treatment or craniotomy and clipping. We undertook a randomised, multicentre trial to ...
Lymphocyte-specific protein tyrosine kinase (LCK) is a lymphoid-specific, Src family protein tyrosine kinase that is known to play a pivotal role in T-cell activation and interact with the T-cell coreceptors, CD4 and ...
Background: Whereas recent data from imaging studies challenge the prevailing notion that multiple sclerosis (MS) is purely an inflammatory disease, pathologic studies suggest differences in the disease processes betw...
Background and Purpose -The Vitamin Intervention for Stroke Prevention trial (VISP) intention-to-treat analysis did not show efficacy of combined vitamin therapy for recurrent vascular events in patients with nondisab...
Information about 255 children and adults with Pompe disease was gathered thr ough a questionnaire. Disease severity was associated with disease duration and not with age; an early manifestation of the disease implied...
Background: There is growing evidence from case-control and from cohort studi es that smoking is inversely related to the risk of developing Parkinson’s dise ase (PD). However, it is still controversial if PD starts ...
Objective: To investigate the heterogeneity of idiopathic Parkinson’s disease (PD) in a data driven manner among a cohort of patients in the early clinical s tages of the disease meeting established diagnostic criter...
Objective: To assess the efficacy of interferon beta-1b (IFNβ-1b) in Japane se patients with relapsing-remitting multiple sclerosis (RRMS). Background: The effects of IFNβin RRMS have been assessed in study populati...
Introduction. Hematological diseases are seldom found as the etiology of isch emic strokes, but are frequently investigated by expensive laboratory tests afte r a first cerebral vascular event. Methods. In the Lausann...
BACKGROUND: Tuberculous meningitis kills or disables more than half of those a ffected with the disease. Previous studies have been too small to determine whet her adjunctive treatment with corticosteroids can reduce ...