supported by the National Natural Science Foundation of China(82088102);Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2019-I2M-5-064);Collaborative Innovation Program of Shanghai Municipal Health Commission(2020CXJQ01);Clinical Research Plan of Shanghai Hospital Development Center(SHDC2020CR1008A);Shanghai Frontiers Science Research Base of Reproduction and Development;Zhejiang Provincial Natural Science Foundation of China(LQ21H040005)。
The events occurring before and soon after birth appear to impact an individual’s health throughout adulthood significantly.The pioneering work of David J.P.Barker studied the nutritional status of 2414 pregnant wome...
supported by the National Natural Science Foundation of China(31570832);the National Program on Key Basic Research Project of China(2014CB9103000/02);Science and Technology Department of Hunan Province(2018RS3086);National Postdoctoral Program for Innovative Talents(BX201700306);China Postdoctoral Science Foundation(2018M632127);the Hunan Provincial Natural Science Foundation(2017JJ2198,2018JJ1012);Guangxi Funds for Distinguished Experts
P2X receptors are a family of extracellular ATP-gated trimeric cation channels that is widely distributed in human tissues. Quite some drug candidates targeting P2X receptors have entered into preclinical or main phas...
supported by the National Natural Science Foundation of China(31160304);Gansu Provincial Key Laboratory of Aridland Crop Science,Gansu Agricultural University,China
It was reported that exogenous hydrogen peroxide (H2O2) can induce primary root bend in Arabidopsis and pea. However, the mechanism remains unclear. Here we explored the mechanism underlying this phenomenon by using...
Several methods of interval mapping of QTLs underlying endosperm traits based on random hybridization designs and the triploid genetic model are proposed. The basic idea is: plants (or lines) from a population with kn...
A novel neural model for emotional modulation of word reading is proposed. This model has four principal hypotheses: the dominant activa-tion region hypothesis, the emotional modulation hypothesis, the attentional lev...
supported by the National Natural Science Foundation of China(Grant Nos.39900080,30270724&30370758).
Genetic expression for an endosperm trait in seeds of cereal crops may be controlled simultaneously by the triploid endosperm genotypes and the diploid maternal genotypes. However, current statistical methods for mapp...
The extraordinarily preserved, diverse arthropod fauna from the Lower Cambrian Maotianshan shale,central Yunnan (southwest China), represents different evolutionary stages stepping from stem lineages towards crown art...
This work was supported by the National Natural Science Foundation of China (Grant Nos. 30170379 and 39870356).
To study the regulation of angiotensin Ⅱ (Ang Ⅱ) on Gαq/11 protein of vascular smooth muscle cell (VSMC) and its underlying mechanism, the protein synthesis was detected by [3H]-leucine incorporation. Gαq/11 expre...
An oriented graph is a digraph without loops, multiple arcs or cycles of length 2. Let D=(V, A) be an oriented graph of the order p, where V and A denote the set of vertices and the set of arcs of D, respectively. Ass...
In case-control studies, controls are often more readily obtained than cases so it makes sense to have the control-case ratio larger than 1. In case-control design, for the basic form of one dichtomous risk factor, we...