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作品数:543被引量:706H指数:12
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相关领域:医药卫生更多>>
相关作者:李博黄澄如胡道予高艳梅刘苗更多>>
相关机构:山东大学华中科技大学中国科学院北京大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金北京市自然科学基金更多>>
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Regional Differences of the Urinary Proteomes in Healthy Chinese Individuals被引量:2
《Chinese Medical Sciences Journal》2019年第3期157-167,共11页吴建强 秦伟伟 潘利 王小蓉 张彪 单广良 高友鹤 
supported by the Key Basic Research Program of the Ministry of Science and Technology of China(No.2013FY114100);the National Key Research and Development Program of China(No.2018YFC0910202,2016YFC1306300);the Beijing Natural Science Foundation(No.7172076);the Beijing Cooperative Construction Project(No.110651103);Beijing Normal University(No.11100704);Peking Union Medical College Hospital(2016-2.27)
Objective Urine is a promising biomarker source for clinical proteomics studies.Regional physiological differences are common in multi-center clinical studies.In this study,we investigate whether significant differenc...
关键词:URINE PROTEOMICS BIOBANK biomarkers regional differences 
Early urinary candidate biomarker discovery in a rat thioacetamide-induced liver fibrosis model被引量:3
《Science China(Life Sciences)》2018年第11期1369-1381,共13页Fanshuang Zhang Yanying Ni Yuan Yuan Wei Yin Youhe Gao 
supported by the National Key Research and Development Program of China (2016YFC1306300);the National Basic Research Program of China (2013CB530850), Beijing Natural Science Foundation (7173264, 7172076);Funds from Beijing Normal University (11100704, 10300-310421102)
Biomarker is the change associated with the disease. Blood is relatively stable because of the homeostatic mechanisms of the body. However, urine accumulates changes of the body, which makes it a better early biomarke...
关键词:URINE proteomics biomarker animal MODEL liver FIBROSIS 
Urinary metabonomics study of Wu-tou-tang and its co-decoction with Pinelliae Rhizoma in adjuvant-induced arthritis rats被引量:6
《Chinese Chemical Letters》2015年第3期387-392,共6页Yao Qi Zi-Feng Pi Shu Liu Feng-Rui Song Ying Xu Na Lin Zhi-Qiang Liu 
supported by the National Basic Research Program of China (973 Program,Nos.2011CB505300,2011CB505305)
Wu-tou-tang was applied to treat rheumatoid arthritis,rheumatic arthritis,and joint pain for thousands of years.Aconiti Radix Cocta is the primary component of Wu-tou-tang,and Aconiti Radix and Pinelliae Rhizoma is on...
关键词:decoction adjuvant Radix endogenous rheumatic urine metabolism taboo urinary quantify 
Effects of Three Commonly-used Diuretics on the Urinary Proteome被引量:1
《Genomics, Proteomics & Bioinformatics》2014年第3期120-126,共7页Xundou Li Mindi Zhao Menglin Li Lulu Jia Youhe Gao 
supported by the National Basic Research Program of China(Grant Nos.2012CB517606 and2013CB530805);111 Project(Grant No.B08007),National Natural Science Foundation of China(Grant No.31200614);Beijing Natural Science Foundation(Grant No.5132028);Key Basic Research Program of the Ministry of Science and Technology of China(Grant No.2013FY114100)
Biomarker is the measurable change associated with a physiological or pathophysiological process. Unlike blood which has mechanisms to keep the internal environment homeostatic, urine is more likely to reflect changes...
关键词:Urinary proteome DIURETICS Biomarkers 
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