目的利用肝螺杆菌(Helicobacter hepaticus,H.hepaticus)致维生素D受体(vitamin D receptor,VDR)缺陷小鼠肠纤维化,构建炎性肠病模型,初步探究其病理特征及发病机制。方法用2×10^(8)CFU的H.hepaticus菌液灌胃野生型和VDR^(-/-)雄性小鼠...
supported by grants from the National Natural Science Foundation of China(grants No.81873713 and No.U22A20157)。
The consumption of a high-fat diet(HFD)has been linked to osteoporosis and an increased risk of fragility fractures.However,the specific mechanisms of HFD-induced osteoporosis are not fully understood.Our study shows ...